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Complex partial status epilepticus
Classification and external resources
ICD-10 G41.2
eMedicine neuro/114
MeSH D013226

Complex partial status epilepticus (CPSE) is one of the non-convulsive forms of status epilepticus, a rare form of epilepsy defined by its recurrent nature. CPSE is characterized by seizures involving long-lasting stupor, staring and unresponsiveness.[1] Sometimes this is accompanied by motor automatisms, such as eye twitching.[2]



As is the case with other non-convulsive status epilepticus forms, CPSE is dangerously underdiagnosed.[3] This is due to the potentially fatal yet veiled nature of the symptoms. Usually, an electroencephalogram, or EEG, is needed to confirm a neurologist's suspicions. The EEG is also needed to differentiate between absence status epilepticus (which affects the entire brain), and CPSE, which only affects one region.[4]


Treatment is in the form of anti-epileptic drugs, such as barbiturates, benzodiazepines and topiramate.


  1. ^ neuro/114 at eMedicine
  2. ^ Fernández-Torre JL, Gutiérrez-Pérez R, Velasco-Zarzosa M (2003). "Non-convulsive status epilepticus" (in Spanish; Castilian). Revista de neurologia 37 (8): 744–52. PMID 14593634.  
  3. ^ Murthy JM (1 October 2003). "Nonconvulsive status epilepticus: An under diagnosed and potentially treatable condition". Neurology India 51 (4): 453–4. PMID 14742920.;year=2003;volume=51;issue=4;spage=453;epage=454;aulast=Murthy.  
  4. ^ Husain AM, Horn GJ, Jacobson MP (2003). "Non-convulsive status epilepticus: usefulness of clinical features in selecting patients for urgent EEG". J. Neurol. Neurosurg. Psychiatr. 74 (2): 189–91. doi:10.1136/jnnp.74.2.189. PMID 12531946. PMC 1738268.  

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