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Controlled Drug: Wikis


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The United Kingdom Misuse of Drugs Act 1971 aimed to control the possession and supply of numerous listed drugs and drug-like substances as a controlled substance. The act allowed and regulated the use of some Controlled Drugs (designated CD) by various classes of persons (e.g. doctors) acting in their professional capacity.

In clinical practice, this mostly applies to the use of strong opiates for pain management and some amphetamine-like stimulants used for Attention-deficit hyperactivity disorder; both of which are regulated under Schedule 2.

The Royal Pharmaceutical Society of Great Britain maintains a live database that allows you to check the Legal Classification of Medicines.



Special responsibilities are placed upon pharmaceutical wholesalers, pharmacies and doctors in the stocking, distribution, issuing of prescriptions, supply and disposal of items listed under the first three of the schedules. The regulations have been further tightened since Dr Harold Shipman used diamorphine to murder hundreds of his patients during the late 20th century.

Schedule 1 - CD Lic

Drugs which are not used medically, and thus their possession and supply is prohibited; e.g. cannabis and LSD except when licenced by the Home Office to carry out research.

Recently, in a report published in The Lancet Journal, researchers have introduced an alternative method for drug classification in the UK. This new system uses a “nine category matrix of harm, with an expert Delphic procedure, to assess the harms of a range of illicit drugs in an evidence-based fashion.” The new classification system suggested that alcohol and tobacco were in the mid-range of harm, while Cannabis, LSD, and Ecstasy were all below the two legal drugs in harmfulness. [1] This research is in line with a British House Of Commons report Drug Classification: Making A Hash Of It.

Schedule 2 - CD

Substances subject to the full controlled drug requirements; e.g. diamorphine (heroin), pethidine, cocaine, methadone, methylphenidate, dextroamphetamine, fentanyl and oxycodone. Prescriptions have previously had to be written out by hand with full details of the form and strength of the preparation. The total quantity has to be written out in both words and figures. It is an offence for a doctor to issue an incomplete prescription or for a pharmacist to dispense a controlled drug unless all the required details are given.

It is the prescriber's responsibility to minimize the risk of dependence or misuse by ensuring that such drugs are not started for a particular patient without good cause, that the dose is not increased to the point where dependency is more likely, and to avoid being an unwitting source of supply for addicts. The quantities of controlled drugs prescribed should match the likely needs of the patients until the next clinical review and prescription forms should be secured against theft.

The safe custody requirements ensures that pharmacists and doctors holding stock of controlled drugs must store them in securely fixed double-locked steel safety cabinets and maintain a written register, which must be bound and contain separate entries for each drug and must be written in ink with no use of correction fluid. Disposal of expired stock must be witnessed by a designated inspector (either a local drug-enforcement police officer or official from health authority).

Schedule 3 - CD No Reg

Include drugs subject to the same prescription requirements as Schedule 2 drugs, but without the requirement to maintain registers; e.g. barbiturates and temazepam. Phenobarbitone is exempt from the requirement of prescriptions needing to be fully written out by hand, although the date must still be hand written. With the exception of phenobarbitone or related drugs for treatment of epilepsy, no Sch 3 drug can be given as an emergency supply. Safe custody is required for Tenuate Dospan, buprenorphine products, temazepam, flunitrazepam (rohypnol) and midazolam. Other Sch 3 drugs can be stored in the general dispensary.

Schedule 4

Controlled drug prescription requirements and safe custody requirements do not apply. Included drugs are Benzodiazepines (Subclass CD Benz), other than temazepam, flunitrazepam or midazolam, and androgenic and anabolic steroids (Subclass CD Anab). However CD Benz products- which also include mild stimulants such as mesocarb and femcamfamine, formerly prescribed as anorectics- are illegal to supply or possess without prescription and all Sch 4 drugs cannot be legally supplied without medical authority.

Schedule 5 - CD Inv

Includes items, which because of their strength are exempt from all requirements other than the need to retain invoices for two years.


  1. ^ Nutt D, King LA, Saulsbury W, Blakemore C (March 2007). "Development of a rational scale to assess the harm of drugs of potential misuse". Lancet 369 (9566): 1047–53. doi:10.1016/S0140-6736(07)60464-4. PMID 17382831.   edit

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