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Coronary disease
Classification and external resources
MeSH D003327

Coronary disease (or coronary heart disease) refers to the failure of coronary circulation to supply adequate circulation to cardiac muscle and surrounding tissue. It is already the most common form of disease affecting the heart and an important cause of premature death in Europe, the Baltic states, Russia, North and South America, Australia and New Zealand. It has been predicted that all regions of the world will be affected by 2020.[1]

It is most commonly equated with atherosclerotic coronary artery disease, but coronary disease can be due to other causes, such as coronary vasospasm.[2] It is possible for the stenosis to be caused by the spasm.[3]


  1. ^ Boon NA, Colledge NR, Walker BR and Hunter JAA (2006). Davidson's Principles & Practice of Medicine, 20th Edition. Churchill Livingstone
  2. ^ Williams MJ, Restieaux NJ, Low CJ (February 1998). "Myocardial infarction in young people with normal coronary arteries". Heart 79 (2): 191–4. PMID 9538315.  
  3. ^ Rezkalla SH, Kloner RA (October 2007). "Cocaine-induced acute myocardial infarction". Clin Med Res 5 (3): 172–6. doi:10.3121/cmr.2007.759. PMID 18056026.  


Simple English

Coronary heart disease, also called coronary artery disease, is a progressive reduction of blood to the heart muscle because of the narrowing of the coronary artery. It is caused by a build-up of atheromatous plaques inside the arteries that deliver blood to the myocardium (the muscular tissue of the heart). Most people with coronary heart disease can look well for years before they start experiencing symptoms, often a heart attack. If it goes untreated, some of the atheromatous plaques might break away and block the blood flow to the heart. Coronary heart disease is the most common cause of sudden death, and it is also the most common cause of death in people over 65 years old. Men are 10 times more likely to suffer from coronary heart disease than women.Yet it kills a lot of people.

Impairment of heart function due to the blood flow to the heart compared to its needs, caused by obstruction changes in coronary circulation of the heart.


Atherosclerosis is a form of cardiovascular disease. It is where fatty materials (such as cholesterol) build up in the arteries constricting blood flow due to a blood clot. The artery walls also constrict due to the presence of foam cell. These are created when Low-Density Lipoproteins diffuse through the artery walls and become oxidised by free radicals. White blood cells then try to ingest the oxidised cholesterol which creates the foam cells. If a complete blockage of an artery occurs then this prevents cells from receiving oxygen and nutrients and the cells will die. This is bad in any case but especially if it happens in the coronary arteries. This will result in a section of the heart dieing and a myocardial infraction (heart attack) may occur.

Preventative measures

  • Dietary changes such as reduction of fat, limited consumption of saturated fats
  • An increase in the consumption of vegetables, fruits, legumes and whole grains
  • Avoidance of alcohol, salt intake, alcohol
  • Regular physical activity
  • Obesity reduction by weight control



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