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Cyclazocine: Wikis

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Cyclazocine
Systematic (IUPAC) name
10-(cyclopropylmethyl)- 1,13-dimethyl- 10-azatricyclo [7.3.1.02,7] trideca- 2(7),3,5- trien- 4-ol
Identifiers
CAS number 3572-80-3
ATC code none
PubChem 19143
Chemical data
Formula C 18H25NO 
Mol. mass 271.397 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Cyclazocine is a mixed opiate agonist-antagonist related to dezocine, pentazocine and phenazocine. This family of opioid drugs is called the benzomorphans or benzazocines.

Use

Research into the use of cyclazocine for the treatment of Bipolar patients with depression was undertaken by Fink and colleagues (1970). It showed that 8 out of 10 patients experienced moderate improvement.

Research during the 1960s and 1970s into the possible use of cyclazocine for management of pain, and later for assisting treatment of narcotic addiction was severely hampered by the drug's psychotomimetic, dysphoric, and hallucinatory effects.

Dosage

Dosages of 1–3 mg were administered in the tests.

See also

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