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Cyclic nucleotide-gated channel alpha 2: Wikis


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Cyclic nucleotide gated channel alpha 2
External IDs OMIM300338 MGI108040 HomoloGene32022 IUPHAR: CNGA2 GeneCards: CNGA2 Gene
Species Human Mouse
Entrez 1260 12789
Ensembl ENSG00000183862 ENSMUSG00000005864
UniProt Q16280 Q80XH6
RefSeq (mRNA) NM_005140 NM_007724
RefSeq (protein) NP_005131 NP_031750
Location (UCSC) Chr X:
150.65 - 150.66 Mb
Chr X:
68.24 - 68.26 Mb
PubMed search [1] [2]

Cyclic nucleotide gated channel alpha 2, also known as CNGA2, is a human gene encoding an ion channel protein.[1]


See also


Further reading

  • Trudeau MC, Zagotta WN (2003). "Calcium/calmodulin modulation of olfactory and rod cyclic nucleotide-gated ion channels.". J. Biol. Chem. 278 (21): 18705–8. doi:10.1074/jbc.R300001200. PMID 12626507.  
  • Hofmann F, Biel M, Kaupp UB (2006). "International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels.". Pharmacol. Rev. 57 (4): 455–62. doi:10.1124/pr.57.4.8. PMID 16382102.  
  • Distler M, Biel M, Flockerzi V, Hofmann F (1995). "Expression of cyclic nucleotide-gated cation channels in non-sensory tissues and cells.". Neuropharmacology 33 (11): 1275–82. doi:10.1016/0028-3908(94)90027-2. PMID 7532814.  
  • Finn JT, Krautwurst D, Schroeder JE, et al. (1998). "Functional co-assembly among subunits of cyclic-nucleotide-activated, nonselective cation channels, and across species from nematode to human.". Biophys. J. 74 (3): 1333–45. doi:10.1016/S0006-3495(98)77846-4. PMID 9512030.  
  • Sautter A, Zong X, Hofmann F, Biel M (1998). "An isoform of the rod photoreceptor cyclic nucleotide-gated channel beta subunit expressed in olfactory neurons.". Proc. Natl. Acad. Sci. U.S.A. 95 (8): 4696–701. doi:10.1073/pnas.95.8.4696. PMID 9539801.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Yoo D, Flagg TP, Olsen O, et al. (2004). "Assembly and trafficking of a multiprotein ROMK (Kir 1.1) channel complex by PDZ interactions.". J. Biol. Chem. 279 (8): 6863–73. doi:10.1074/jbc.M311599200. PMID 14604981.  
  • Cheng KT, Chan FL, Huang Y, et al. (2004). "Expression of olfactory-type cyclic nucleotide-gated channel (CNGA2) in vascular tissues.". Histochem. Cell Biol. 120 (6): 475–81. doi:10.1007/s00418-003-0596-2. PMID 14618336.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Qu W, Moorhouse AJ, Chandra M, et al. (2006). "A single P-loop glutamate point mutation to either lysine or arginine switches the cation-anion selectivity of the CNGA2 channel.". J. Gen. Physiol. 127 (4): 375–89. doi:10.1085/jgp.200509378. PMID 16533895.  

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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