The Full Wiki

More info on Cyclin B

Cyclin B: Wikis


Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.


From Wikipedia, the free encyclopedia

cyclin B1
Symbol CCNB1
Alt. symbols CCNB
Entrez 891
HUGO 1579
OMIM 123836
RefSeq NM_031966
UniProt P14635
Other data
Locus Chr. 5 q12
cyclin B2
Symbol CCNB2
Entrez 9133
HUGO 1580
OMIM 602755
RefSeq NM_004701
UniProt O95067
Other data
Locus Chr. 15 q21.3
cyclin B3
Symbol CCNB3
Entrez 85417
HUGO 18709
OMIM 300456
RefSeq NM_033670
UniProt Q8WWL7
Other data
Locus Chr. X p11

Cyclin B is a member of the cyclin family.

Cyclin B is a mitotic cyclin. The amount of cyclin B (which binds to Cdk1) and the activity of the cyclin B-Cdk complex rise through the cell cycle[1] until mitosis, where they fall abruptly due to degradation.[2] The complex of Cdk and cyclin B is called maturation promoting factor or mitosis promoting factor (MPF).

Expression of cyclins through the cell cycle.

See also


  1. ^ Ito M (August 2000). "Factors controlling cyclin B expression". Plant Mol. Biol. 43 (5-6): 677–90. PMID 11089869.  
  2. ^ Hershko A (September 1999). "Mechanisms and regulation of the degradation of cyclin B". Philos. Trans. R. Soc. Lond., B, Biol. Sci. 354 (1389): 1571–5; discussion 1575–6. doi:10.1098/rstb.1999.0500. PMID 10582242.  

External links



Got something to say? Make a comment.
Your name
Your email address