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Cyclopentenone prostaglandin: Wikis


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Cyclopentenone prostaglandin (cyPG) is a type of prostaglandin, a molecule which regulates inflammation and other processes. It is a potential new target for anti-inflammatory actions. It is thought to prevent the inflammatory pathway by inhibiting the activation of NF-κB, a transcription factor in cell reproduction.

The cyclopentenone prostaglandin known as 15d-PGJ2 has been shown to inhibit a gene in T cells which is active in inflammation, such as in various autoimmune diseases.[1][2]



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