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D-Deprenyl: Wikis

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D-Deprenyl
Systematic (IUPAC) name
(2S)-N-methyl-1-phenyl-N-prop-2-ynyl-propan-2-amine
Identifiers
ATC code  ?
Chemical data
Formula C13H17N 
Mol. mass 187.28 g/mol
Therapeutic considerations
Pregnancy cat.  ?
Legal status

D-Deprenyl, also known as or dextro-N-propargyl-N-methylamphetamine, is an MAO-B inhibitor, as well as prodrug to d-amphetamine and d-methamphetamine, and therefore a norepinephrine-dopamine releasing agent. It is the opposite enantiomer of l-deprenyl (selegiline).

L-Deprenyl, also an MAO-B inhibitor, metabolizes to l-amphetamine and l-methamphetamine, which are selective norepinephrine releasing agents. In contrast, d-deprenyl additionally has dopaminergic effects and has been found to be reinforcing in scientific research, whereas l-deprenyl is the opposite.[1]

See also

References

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