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D site of albumin promoter (albumin D-box) binding protein
Identifiers
Symbols DBP; DABP
External IDs OMIM124097 MGI94866 HomoloGene1035 GeneCards: DBP Gene
RNA expression pattern
PBB GE DBP 209782 s at tn.png
PBB GE DBP 209783 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 1628 13170
Ensembl ENSG00000105516 ENSMUSG00000059824
UniProt Q10586 Q3USN7
RefSeq (mRNA) NM_001352 NM_016974
RefSeq (protein) NP_001343 NP_058670
Location (UCSC) Chr 19:
53.83 - 53.83 Mb
Chr 7:
45.57 - 45.58 Mb
PubMed search [1] [2]

D site of albumin promoter (albumin D-box) binding protein, also known as DBP, is a protein which in humans is encoded by the DBP gene.[1][2]

DBP is a member of the PAR bZIP (Proline and Acidic amino acid-Rich basic leucine ZIPper) transcription factor family.[3][1] DBP binds to a upstream promoter in the insulin gene.[4]

References

  1. ^ a b "Entrez Gene: DBP D site of albumin promoter (albumin D-box) binding protein". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1628.  
  2. ^ Szpirer C, Riviere M, Cortese R, Nakamura T, Islam MQ, Levan G, Szpirer J (June 1992). "Chromosomal localization in man and rat of the genes encoding the liver-enriched transcription factors C/EBP, DBP, and HNF1/LFB-1 (CEBP, DBP, and transcription factor 1, TCF1, respectively) and of the hepatocyte growth factor/scatter factor gene (HGF)". Genomics 13 (2): 293–300. doi:10.1016/0888-7543(92)90245-N. PMID 1535333. http://linkinghub.elsevier.com/retrieve/pii/0888-7543(92)90245-N.  
  3. ^ Khatib ZA, Inaba T, Valentine M, Look AT (September 1994). "Chromosomal localization and cDNA cloning of the human DBP and TEF genes". Genomics 23 (2): 344–51. doi:10.1006/geno.1994.1510. PMID 7835883.  
  4. ^ Melloul D, Marshak S, Cerasi E (March 2002). "Regulation of insulin gene transcription". Diabetologia 45 (3): 309–26. doi:10.1007/s00125-001-0728-y. PMID 11914736.  

Further reading

  • Brown SA, Schibler U (1999). "The ins and outs of circadian timekeeping.". Curr. Opin. Genet. Dev. 9 (5): 588–94. doi:10.1016/S0959-437X(99)00009-X. PMID 10508692.  
  • Szpirer C, Riviere M, Cortese R, et al. (1992). "Chromosomal localization in man and rat of the genes encoding the liver-enriched transcription factors C/EBP, DBP, and HNF1/LFB-1 (CEBP, DBP, and transcription factor 1, TCF1, respectively) and of the hepatocyte growth factor/scatter factor gene (HGF).". Genomics 13 (2): 293–300. doi:10.1016/0888-7543(92)90245-N. PMID 1535333.  
  • Khatib ZA, Inaba T, Valentine M, Look AT (1995). "Chromosomal localization and cDNA cloning of the human DBP and TEF genes.". Genomics 23 (2): 344–51. doi:10.1006/geno.1994.1510. PMID 7835883.  
  • Nyunoya H, Morita T, Sato T, et al. (1994). "Cloning of a cDNA encoding a DNA-binding protein TAXREB302 that is specific for the tax-responsive enhancer of HTLV-I.". Gene 148 (2): 371–3. doi:10.1016/0378-1119(94)90716-1. PMID 7958972.  
  • Nyunoya H, Morita T, Sato T, et al. (1993). "Cloning of a cDNA encoding a DNA-binding protein TAXREB302 that is specific for the tax-responsive enhancer of HTLV-I.". Gene 126 (2): 251–5. doi:10.1016/0378-1119(93)90375-D. PMID 8482542.  
  • Picketts DJ, Lillicrap DP, Mueller CR (1993). "Synergy between transcription factors DBP and C/EBP compensates for a haemophilia B Leyden factor IX mutation.". Nat. Genet. 3 (2): 175–9. doi:10.1038/ng0293-175. PMID 8499951.  
  • Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction.". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.  
  • Shutler G, Glassco T, Kang X, et al. (1996). "Genomic structure of the human D-site binding protein (DBP) gene.". Genomics 34 (3): 334–9. doi:10.1006/geno.1996.0295. PMID 8786133.  
  • Stubbs L, Carver E, Ashworth L, Lopez-Molina L (1997). "Location of the DBP transcription factor gene in human and mouse.". Mamm. Genome 7 (1): 65–7. doi:10.1007/s003359900016. PMID 8903733.  
  • Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing.". Genome Res. 7 (4): 353–8. PMID 9110174.  
  • Begbie M, Mueller C, Lillicrap D (1999). "Enhanced binding of HLF/DBP heterodimers represents one mechanism of PAR protein transactivation of the factor VIII and factor IX genes.". DNA Cell Biol. 18 (2): 165–73. doi:10.1089/104454999315556. PMID 10073576.  
  • Lamprecht C, Mueller CR (1999). "D-site binding protein transactivation requires the proline- and acid-rich domain and involves the coactivator p300.". J. Biol. Chem. 274 (25): 17643–8. doi:10.1074/jbc.274.25.17643. PMID 10364202.  
  • Yan L, Miyake S, Okamura H (2000). "Distribution and circadian expression of dbp in SCN and extra-SCN areas in the mouse brain.". J. Neurosci. Res. 59 (2): 291–5. doi:10.1002/(SICI)1097-4547(20000115)59:2<291::AID-JNR16>3.0.CO;2-O. PMID 10650888.  
  • Smith JS, Tachibana I, Pohl U, et al. (2000). "A transcript map of the chromosome 19q-arm glioma tumor suppressor region.". Genomics 64 (1): 44–50. doi:10.1006/geno.1999.6101. PMID 10708517.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Newman JR, Keating AE (2003). "Comprehensive identification of human bZIP interactions with coiled-coil arrays.". Science 300 (5628): 2097–101. doi:10.1126/science.1084648. PMID 12805554.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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