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DPI-287: Wikis

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DPI-287
Systematic (IUPAC) name
4-[(R)-[(2S,5R)-2,5-dimethyl-4-benzylpiperazin-1-yl]-(3-hydroxyphenyl)methyl]-N,N-diethylbenzamide
Identifiers
CAS number  ?
ATC code  ?
PubChem 21025820
Chemical data
Formula C 31H39N3O2  
Mol. mass 485.659 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

DPI-287 is a drug which is used in scientific research. It is a highly selective agonist for the δ-opioid receptor which produces less convulsions than most drugs from this family.[1] It has antidepressant effects.[2]

References

  1. ^ Jutkiewicz EM. The antidepressant -like effects of delta-opioid receptor agonists. Molecular Interventions. 2006 Jun;6(3):162-9. PMID 16809477
  2. ^ Jutkiewicz EM, Chang KJ, Rice KC, Woods JH. (2005) Characterization of a novel nonpeptide delta-opioid agonist analog DPI287 with antidepressant-like activity. Experimental Biology meeting abstracts. FASEB J. 19, Abstract # 874.4
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