Resin was born in South Bend, Indiana. He was three years old when his parents divorced. Resin met his future wife, Maggie, in the seventh grade. He graduated from Indiana University in 1954. While at Indiana University, Dan became a member of the Alpha Iota Chapter of the Theta Chi Fraternity. Shortly after graduation, he was drafted into the military, where he served in Fort Monmouth, New Jersey. After his discharge, he finished college at Columbia University in New York City.
He worked an assortment of jobs from singer to Master of Ceremonies at the Roxy Theater and later, Radio City Music Hall. Dan and Maggie lived in Weehawken and Union City until 1959, when they bought a home in Secaucus, New Jersey. They have a summer home on North Lake in Dingmans Ferry, Pennsylvania.It is on a beautiful lake for drinking wine spritzers and watching the sun go down.
Dan played many roles on Broadway such as Freddie Eynsford-Hill in My Fair Lady (1956). Resin also appeared in the original off-Broadway production of Once Upon a Mattress, and continued with the show when it made a successful move to Broadway. His stage productions include Don't Drink the Water, On a Clear Day You Can See Forever, Fade Out - Fade In, and Young Abe Lincoln.
Resin's most famous movie role was as Dr. Beeper in the comedy film Caddyshack (1980). His other movie roles included Wise Guys, The Sunshine Boys, The Private Files of J. Edgar Hoover, The Happy Hooker (1975) and other films. Resin played the role of a young Richard Nixon in the 1972 parody film, Richard.
His television career included a CBS show, On Our Own; the soap opera Edge of Night; Lovers and Friends; David Frost Review; and an NBC show, Go USA. He made appearances on the kids show Captain Kangaroo, and was featured in the 1978 syndicated comedy Madhouse Brigade.
Resin seems best remembered by the public for his roles in TV commercials, where he specialized in strange, humorous characters and situations such as the Tidy Bowl Man. Another role for which Resin is known was for a cream cheese, in which he played an elegant diner in a posh restaurant.
Resin made a living through commercials, and at the peak of his career in the 1970s and 1980s he was doing as many as two and three commercials a week. In fact, he had two commercials back to back during one of the Super Bowls, a feat he believes is unequaled.
After semi-retirement from acting, he became a Eucharistic Minister.
His acting roles include Music Box, The Man With One Red Shoe, Deadhead Miles, If Ever I See You Again, Remember WENN, Judith Krantz's Till We Meet Again, That's Adequate, Soggy Bottom USA, God Told Me To, Crazy Joe, Hail, and New York Undercover among others.