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Deer tick virus
Black and white microphotograph of Feulgen stained, intact tick salivary glands infected by deer tick virus. Hypotrophied salivary acinus filled with amorphous masses of pinkstaining (=Feulgen positive) material (arrows). Scale bar = 10 µm.
Virus classification
Group: Group IV ((+)ssRNA)
Family: Flaviviridae
Genus: Flavivirus
Species: Powassan virus

Deer tick virus is a virus causing tick-borne encephalitis.[1]

Deer tick virus is a flavivirus closely resembling Powassan virus (to which it has 94% amino acid sequence identity).[2][3] Because they are so related, deer tick virus is thought to be a genotype of Powassan virus, and also called Powassan virus lineage II.[4]

In 1997, it was isolated from Ixodes scapularis (the deer tick, formerly Ixodes dammini) collected in Massachusetts and Connecticut.[5]


Phylogram indicating the relationship of deer tick virus to other tick-borne encephalitis group viruses.TBE, tick borne encephalitis; TSE, Turkish sheep encephalitis; GGE, Greek goat encephalitis; LI, louping ill virus; SSE, Spanish sheep encephalitis; KFD, Kyasanur Forest disease virus; TYU, Tyuleniy virus; SRE, Saumarez Reef virus.
Values above branches indicate bootstrapped confidence values. Branch lengths are proportional to percent similarity in sequence.

See also


  1. ^ Tavakoli NP, Heng W, Dupuis M et al (2009). "Fatal Case of Deer Tick Virus Encephalitis". N. Engl. J. Med.. 360: 2099-2107.
  2. ^ Kuno G, Artsob H, Karabatsos N, Tsuchiya KR, Chang GJ (November 2001). "Genomic sequencing of deer tick virus and phylogeny of powassan-related viruses of North America". Am. J. Trop. Med. Hyg. 65 (5): 671–6. PMID 11716135.  
  3. ^ Beasley DW, Suderman MT, Holbrook MR, Barrett AD (November 2001). "Nucleotide sequencing and serological evidence that the recently recognized deer tick virus is a genotype of Powassan virus". Virus Res. 79 (1-2): 81–9. PMID 11551648.  
  4. ^ Ebel GD, Spielman A, Telford SR (July 2001). "Phylogeny of North American Powassan virus". J. Gen. Virol. 82 (Pt 7): 1657–65. PMID 11413377.  
  5. ^ Telford SR, Armstrong PM, Katavolos P, et al (1997). "A new tick-borne encephalitis-like virus infecting New England deer ticks, Ixodes dammini". Emerging Infect. Dis. 3 (2): 165–70. PMID 9204297.  


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