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Demecarium bromide
Systematic (IUPAC) name
trimethyl-[3-[methyl-[10-[methyl- (3-trimethylammoniophenoxy) carbonyl-amino] decyl] carbamoyl] oxyphenyl]-ammonium dibromide
Identifiers
CAS number 56-94-0
ATC code S01EB04
PubChem 5965
DrugBank APRD00905
Chemical data
Formula C 32H52Br2N4O4  
Mol. mass 716.588 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?
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Demecarium is a parasympathomimetic that acts as an acetylcholinesterase inhibitor. It is one of several topical (applied directly to the affected area) medications used to reduce elevated intraocular pressure (IOP) associated with primary glaucoma in cats, dogs, and other animals.[1][2][3]

See also

References

  1. ^ Ward D, Abney K, Oliver J (2003). "The effects of topical ocular application of 0.25% demecarium bromide on serum acetylcholinesterase levels in normal dogs.". Vet Ophthalmol 6 (1): 23–5. doi:10.1046/j.1463-5224.2003.00257.x. PMID 12641839.  
  2. ^ Krohne S (1994). "Effect of topically applied 2% pilocarpine and 0.25% demecarium bromide on blood-aqueous barrier permeability in dogs.". Am J Vet Res 55 (12): 1729–33. PMID 7887518.  
  3. ^ Gum G, Gelatt K, Gelatt J, Jones R (1993). "Effect of topically applied demecarium bromide and echothiophate iodide on intraocular pressure and pupil size in beagles with normotensive eyes and beagles with inherited glaucoma.". Am J Vet Res 54 (2): 287–93. PMID 8430939.  
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