| -plasia |
|---|
| (Ana)plasia - dedifferentiation |
| (Hyper)plasia - physiological proliferation |
| (Neo)plasia - abnormal proliferation |
| (Dys)plasia - maturation abnormality |
| (Meta)plasia - cell type conversion |
| (Desmo)plasia - connective tissue growth |
In medicine, desmoplasia is the growth of fibrous or connective tissue.[1] It is also called desmoplastic reaction to emphasis that it is secondary to a neoplasm, causing dense fibrosis around the tumor.[1] Also, scar tissue (adhesions) within the abdomen after abdominal surgery is a type of desmoplastic reaction.[1]
Desmoplasia is usually only associated with malignant neoplasms, which can evoke a fibrosis response by invading healthy tissue. Infiltrating metastatic ductal carcinomas of the breast often have a scirrous, stellate appearance caused by desmoplastic formations.
Desmoplasia originates from the Greek desmos (meaning fetter or band) and plasia (meaning to form). It is usually used in the description of desmoplastic small round cell tumors. Neoplasm (or neoplasia) is the medical term used for both benign and malignant tumors. Basically, it's a blanket term that refers to abnormal, excessive, uncoordinated, and autonomous cellular/tissue growth.
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