The Full Wiki

More info on Dexetimide

Dexetimide: Wikis


Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.


From Wikipedia, the free encyclopedia

Systematic (IUPAC) name
CAS number 21888-98-2
ATC code N04AA08
PubChem 21847
ChemSpider 20533
Chemical data
Formula C23H26N2O2 
Mol. mass 362.465 g/mol
SMILES eMolecules & PubChem
Therapeutic considerations
Pregnancy cat.  ?
Legal status

Dexetimide is a piperidine anticholinergic. It is a muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Dexetimide was discovered at Janssen Pharmaceutica in 1968.


  • Dom R, Van Lommel R, Baro F., A quantitative study of neuroleptic-induced extrapyramidal symptoms and their response to dexetimide, a potent and long-acting antiparkinsonian agent, Acta Psychiatrica Scandinavica 1971;47(4):399-410.
  • Huygens H, Vereecken JL, Tanghe A., Dexetimide (R 16470) in the control of neuroleptic-induced extrapyramidal side-effects. Its prophylactic value and duration of action, Psychiatr Neurol Neurochir. 1973 Jul-Aug;76(4):251-9.


Got something to say? Make a comment.
Your name
Your email address