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Diffuse esophageal spasm
Classification and external resources
ICD-9 530.5
DiseasesDB 32060
MedlinePlus 000289
eMedicine med/743
MeSH D015155

Diffuse esophageal spasm (DES) is a condition in which uncoordinated contractions of the esophagus occur. It is thought to result from motility disorders of the esophagus. These spasms do not propel food effectively to the stomach. It can cause dysphagia, regurgitation and chest pain.



Several drugs, including nitroglycerin and calcium channel blockers are used to treat this condition.


It has been reported that very cold or hot beverages can trigger an esophageal spasm. Contrary, rapid swallowing of a liquid often provides immediate relief.


The condition is sometimes referred to as corkscrew esophagus, due to a characteristic appearance of the esophagus as a corkscrew on barium swallow x-rays.

See also

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