The Full Wiki

More info on Dinoxyline

Dinoxyline: Wikis

Advertisements

Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.

Encyclopedia

From Wikipedia, the free encyclopedia

Dinoxyline
Systematic (IUPAC) name
8,9-dihydroxy-1,2,3,11b-tetrahydrochromeno[4,3,2,-de]isoquinoline
Identifiers
ATC code none
PubChem 9819126
Chemical data
Formula C15H13NO3 
Mol. mass 255.268
SMILES eMolecules & PubChem
Therapeutic considerations
Pregnancy cat.  ?
Legal status

Dinoxyline is a synthetic compound developed for scientific research, which acts as a potent full agonist at all five dopamine receptor subtypes.[1][2][3]

References

  1. ^ Grubbs RA, Lewis MM, Owens-Vance C, Gay EA, Jassen AK, Mailman RB, Nichols DE (March 2004). "8,9-dihydroxy-1,2,3,11b-tetrahydrochromeno[4,3,2,-de]isoquinoline (dinoxyline), a high affinity and potent agonist at all dopamine receptor isoforms". Bioorganic & Medicinal Chemistry 12 (6): 1403–12. doi:10.1016/j.bmc.2004.01.008. PMID 15018913. 
  2. ^ Ryman-Rasmussen JP, Nichols DE, Mailman RB (October 2005). "Differential activation of adenylate cyclase and receptor internalization by novel dopamine D1 receptor agonists". Molecular Pharmacology 68 (4): 1039–48. doi:10.1124/mol.105.012153. PMID 15985612. 
  3. ^ Zhang J, Xiong B, Zhen X, Zhang A (March 2009). "Dopamine D1 receptor ligands: where are we now and where are we going". Medicinal Research Reviews 29 (2): 272–94. doi:10.1002/med.20130. PMID 18642350. 
Advertisements

Advertisements






Got something to say? Make a comment.
Your name
Your email address
Message