The Full Wiki

More info on Disopyramide

Disopyramide: Wikis


Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.


From Wikipedia, the free encyclopedia

Systematic (IUPAC) name
CAS number 3737-09-5
ATC code C01BA03
PubChem 3114
DrugBank APRD00507
ChemSpider 3002
Chemical data
Formula C 21H29N3O 
Mol. mass 339.475 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability High
Protein binding 50% to 65%
Metabolism Hepatic (CYP3A4-mediated)
Half life 6.7 hours (range 4 to 10 hours)
Excretion Renal (80%)
Therapeutic considerations
Pregnancy cat. B2(AU) C(US)
Legal status POM (UK) -only (US)
Routes Oral, intravenous
 Yes check.svgY(what is this?)  (verify)

Disopyramide (INN, trade names Norpace and Rythmodan) is an antiarrhythmic medication. It is a Class Ia antiarrhythmic (sodium channel blocker) used in the treatment of ventricular tachycardias. It has no effect on alpha or beta adrenergic receptors. It resembles Quinidine but it has a marked anti-muscarinic effect on the heart, for this reason, it is not considered as a drug of 1st choice. It is also used in ventricular arrhythmia and supraventricular arrhythmia that might follow myocardial infarctions.

Cardiac Adverse Effects

Extracardiac Effects

External links

Got something to say? Make a comment.
Your name
Your email address