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Divaplon: Wikis

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Systematic (IUPAC) name
CAS number 90808-12-1
ATC code none
PubChem 65822
Chemical data
Formula C 17H17N3O2  
Mol. mass 295.336
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Divaplon (RU-32698) is a nonbenzodiazepine, anxiolytic and anticonvulsant drug from the pyrazolopyrimidine family of drugs. It acts as a partial agonist at the "benzodiazepine site" of the GABAA receptor in the brain.[1][2][3]


  1. ^ Feely M, Boyland P, Picardo A, Cox A, Gent JP. Lack of anticonvulsant tolerance with RU 32698 and Ro 17-1812. European Journal of Pharmacology. 1989 May 19;164(2):377-80. PMID 2759183
  2. ^ Sanger DJ, Joly D, Perrault G. Benzodiazepine (omega) receptor partial agonists and the acquisition of conditioned fear in mice. Psychopharmacology (Berlin). 1995 Sep;121(1):104-8. PMID 8539334
  3. ^ Pellón R, Ruíz A, Lamas E, Rodríguez C. Pharmacological analysis of the effects of benzodiazepines on punished schedule-induced polydipsia in rats. Behavioural Pharmacology. 2007 Feb;18(1):81-7. PMID 17218801

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