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Doxefazepam: Wikis

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Systematic (IUPAC) name
CAS number 40762-15-0
ATC code N05CD12
PubChem 38668
DrugBank ?
Chemical data
Formula C 17H14ClFN2O3  
Mol. mass 348.8
Pharmacokinetic data
Bioavailability  ?
Metabolism Hepatic
Half life 3-4 hours[1]
Excretion Renal
Therapeutic considerations
Pregnancy cat.  ?
Legal status Schedule IV(US)
Routes Oral

Doxefazepam (marketed under brand name Doxans) is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It is used therapeutically as a hypnotic.[2] According to Babbini and colleagues in 1975, this derivative of flurazepam was between 2 and 4 times more potent than the latter while at the same time being half as toxic in laboratory animals.[3]

See also


  1. ^
  2. ^ Rodriguez, G; Rosadini; Sannita; Strumia (1984). "Effects of doxefazepam on normal sleep. An EEG and neuropsychological study". Neuropsychobiology 11 (2): 133–9. PMID 6483162.  
  3. ^ Babbini, M.; Torrielli MV, Strumia E, Gaiardi M, Bartoletti M, De Marchi F. (August 1975). "Sedative-hypnotic properties of a new benzodiazepine in comparison with flurazepam. Pharmacological and clinical findings". Arzneimittel-Forschung 25 (8): 1294–1300. PMID 241364.  

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