Dwarfism: Wikis


Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.

Did you know ...

More interesting facts on Dwarfism

Include this on your site/blog:


From Wikipedia, the free encyclopedia

Classification and external resources

A man with what appears to be a form of SED (Spondyloepiphyseal Dysplasia). Note the long fingers. One of the symptoms is a set of characteristic facial features.
ICD-10 E23.0, E34.2, E45.0, Q77.4
ICD-9 253.3, 259.4
DiseasesDB 80
MedlinePlus 001176
MeSH D004392

Dwarfism (pronounced /ˈdwɔrfɪzəm/) is short stature resulting from an abnormal medical condition. It is sometimes defined as an adult height of less than 4 feet 10 inches (147 cm).[1], although this definition is problematic because short stature in itself is not a disease.

Dwarfism can be caused by over 200 distinct medical conditions,[2] and as such the symptoms and characteristics of individual dwarfs vary greatly. In the USA people who are affected by dwarfism are often referred to as little people.[3]

Disproportionate dwarfism is characterized by one or more body parts being relatively large or small in comparison to those of a normal adult, with growth abnormalities in specific areas being apparent. In cases of proportionate dwarfism, the body appears normally proportioned, but is abnormally small. Hypotonia, or a lack of muscle, is common in dwarfs, but intelligence and lifespan are usually normal.

Achondroplasia is a bone growth disorder responsible for 70% of dwarfism cases.[1] In cases of achondroplasia the limbs are disproportionally short compared to the trunk (abdominal area), with the head larger than normal and characteristic facial characteristics. Conditions in humans characterized by disproportional body parts are typically caused by one or more genetic disorders in bone or cartilage development. Extreme shortness in humans with proportional body parts usually has a hormonal cause, such as growth hormone deficiency, once known as "pituitary dwarfism".[3][4]

There is no single treatment for dwarfism. Individual abnormalities such as bone growth disorders can sometimes be treated through surgery, and some hormone disorders can be treated through medication, but in most cases it is impossible to treat all the symptoms of dwarfism. Most of the time lifestyle changes are needed to cope with the effects of dwarfism. In-home devices like specialized furniture are often needed to help people with dwarfism to function normally.[5] Many support groups exist to help sufferers of dwarfism cope with the challenges they face, and to help them develop strategies to become independent.[6]

Dwarfism is a highly visible condition that often carries negative connotations in society. Due to their unusual height, people with dwarfism are often used as spectacles in entertainment or portrayed with stereotypes. For a person with dwarfism, Heightism is a problem that can lead to ridicule as a child and discrimination as an adult.[7][8]

Short stature can be inherited without any coexisting disease. Short stature in the absence of any abnormal medical condition is not generally considered dwarfism. For example, a short man and a short woman who are in normal health will tend to produce children who are also short but in normal health. Ironically, while short parents tend to produce short children, persons with dwarfism may produce children of normal height, if the cause of their dwarfism is not genetically transmissible.



Dwarfism is a medical disorder with the sole requirement being an adult height under 4 feet 10 inches (147 cm) and it is almost always classified as to the underlying condition that is the cause for the short stature. Dwarfism is not necessarily caused by disease or a genetic disorder; it can simply be a naturally occurring consequence of a person's genetics. If dwarfism is caused by a medical disorder, the person is referred to by the underlying diagnosed disorder. Disorders causing dwarfism are often classified by proportionality. Disproportionate dwarfism describes disorders that cause abnormal proportions of the body parts, while proportionate dwarfism results in a generally uniform stunting of the body.

Disorders that cause dwarfism may be classified according to one of hundreds of names, which are usually permutations of the following roots:

  • location
    • rhizomelic = root, e.g., bones of the upper arm or thigh
    • mesomelic = middle, e.g., bones of the forearm or lower leg
    • acromelic = end, e.g., bones of hands and feet.
    • micromelic = entire limbs are shortened
  • source
    • chondro = of cartilage
    • osteo = of bone
    • spondylo = of the vertebrae
    • plasia = form
    • trophy = growth

Examples include achondroplasia, osseous dysplasia, chondrodystrophy, and osteochondrodystrophy.[9]


A typical defining characteristic of dwarfism is an adult height of less than 4 feet 10 inches. Since those afflicted with dwarfism have such a wide range of physical characteristics, oddities in individuals are identified by diagnosing and monitoring the underlying disorders.

Disproportionate dwarfism is characterized by one or more body parts being disproportionately large or small compared to the rest of the body. In achondroplasia the trunk is normally sized with the limbs being disproportionately short, the head being larger than usual, and the forehead being prominent.[4] Facial features are often affected and individual body parts may have problems associated with them. Orthopedic problems can result from multiple conditions such as diastrophic dysplasia and pseudoachondroplasia.

Proportionate dwarfism is marked by body parts being proportional but stunted.[10] Height is significantly below average and there may be long periods without any significant growth. Sexual development is often delayed or impaired into adulthood. Unlike disproportionate dwarfism, mental capacity may be diminished in some cases of proportionate dwarfism. The overall stunted growth can lead to impaired intelligence when compared to the physical age.

Physical maleffects of malformed bones vary according to the specific disease. Many involve joint pain caused by abnormal bone alignment, or from nerve compression (e.g., spinal stenosis).[3] Early degenerative joint disease, exaggerated lordosis or scoliosis, and constriction of spinal cord or nerve roots can cause pain and disability.[11] Reduced thoracic size can restrict lung growth and reduce pulmonary function. Some forms of dwarfism are associated with disordered function of other organs, such as the brain or liver, sometimes severely enough to be more disabling than the abnormal bone growth.[12][13]

Mental effects also vary according to the specific underlying syndrome. In most cases of skeletal dysplasia, such as achondroplasia, mental function is not impaired in any way.[10] However, there are syndromes which can affect the cranial structure and growth of the brain, severely impairing mental capacity. Unless the brain is directly affected by the underlying disorder, there is little to no chance of mental impairment that can be attributed to dwarfism.[14]

The psychosocial disadvantages may be more distressing than the physical symptoms, especially in childhood and adolescence, but people with dwarfism vary greatly in the degree to which social participation and emotional health are affected.

  • Social prejudice against extreme shortness may reduce social and marital opportunities.[15][16]
  • Numerous studies have demonstrated reduced employment opportunities. Severe shortness is associated with lower income.[16]
  • Self-esteem may suffer and family relationships may be affected.
  • Extreme shortness (in the low 2–3 foot [60–90 cm] range) can interfere with ordinary activities of daily living, like driving or using countertops built for taller people. Other symptoms of dwarfism such as bowed knees and unusually short fingers can lead to back problems, difficulty in walking, and handling objects.
  • Children with dwarfism are particularly vulnerable to teasing and ridicule from classmates. Because dwarfism is relatively uncommon, children may feel isolated from their peers.[12]


Dwarfism can result from myriad medical conditions, each with its own separate symptoms and causes. Two disorders, achondroplasia and growth hormone deficiency (also known as pituitary dwarfism), are responsible for the majority of dwarfism cases.[2]



The most recognizable and most common form of dwarfism is achondroplasia, which accounts for 70% of dwarfism cases and produces rhizomelic short limbs, increased spinal curvature, and distortion of skull growth. Achondroplasia is an autosomal dominant disorder caused by the presence of a faulty allele in a person's genome. If a pair of achondroplasia alleles are present, the result is fatal. Achondroplasia is a mutation in the fibroblast growth factor receptor gene 3 (FGFR3), which is an inhibitor that regulates bone growth. In cases of achondroplasia, the FGR3 gene is too aggressive, negatively impacting bone growth.[17]

Growth hormone deficiency

Growth hormone deficiency (GHD) is a medical condition in which the body produces insufficient growth hormone. Growth hormone, also called somatotropin, is a polypeptide hormone which stimulates growth and cell reproduction. If this hormone is lacking, stunted or even halted growth may become apparent. Children with this disorder may grow slowly and puberty may be delayed by several years, or even indefinitely. Growth hormone deficiency has no single definite cause. It can be caused by mutations of specific genes, damage to the pituitary gland, Turner's syndrome, poor nutrition,[18] or even stress (leading to psychogenic dwarfism).


Other causes of dwarfism include spondyloepiphyseal dysplasia congenita, diastrophic dysplasia, pseudoachondroplasia, hypochondroplasia, primordial dwarfism, Turner syndrome, and osteogenesis imperfecta (OI) and hypothyroidism. Severe shortness with skeletal distortion also occurs in several of the Mucopolysaccharidoses and other storage disorders.[19]

Serious chronic illnesses may produce dwarfism as a side effect. Harsh environmental conditions, such as malnutrition, may also produce dwarfism. These types of dwarfism are indirect consequences of the generally unhealthy or malnourished condition of the individual, and not by any specific disease. The dwarfism often takes the form of simple short stature, without any deformities. In societies where poor nutrition is widespread, the average height of the population may be reduced below its genetic potential by the lack of proper nutrition.


Dwarfism is often diagnosed in childhood on the basis of visible symptoms. A physical examination can usually suffice to diagnose certain types of dwarfism, but genetic testing and diagnostic imaging may be used to determine the exact condition.[20] In a person's youth, growth charts that track height can be used to diagnose subtle forms of dwarfism that have no other striking physical characteristics.[2]

Short stature or stunted growth during youth is usually what brings the condition to medical attention. Skeletal dysplasia is usually suspected because of obvious physical features (e.g., unusual configuration of face or shape of skull), because of an obviously affected parent, or because body measurements (arm span, upper to lower segment ratio) indicate disproportion.[20] Bone X-rays are often key to diagnosing a specific skeletal dysplasia, but are not the sole diagnostic tool. Most children with suspected skeletal dysplasias are referred to a genetics clinic for diagnostic confirmation and genetic counseling. Since about the year 2000, genetic tests for some of the specific disorders have become available.[21]

During an initial medical evaluation of shortness, the absence of disproportion and other clues listed above usually indicates causes other than bone dysplasias. Extreme shortness with completely normal proportions sometimes indicates growth hormone deficiency (pituitary dwarfism).[22]

Short stature alone, in the absence of any other abnormalities, may be the result of the distribution of offspring height from short-statured parents, rather than a symptom of any medical condition.[23]


Many types of dwarfism are impossible to prevent because they are genetically caused. Genetic conditions that cause dwarfism may be identified with genetic testing, by screening for the specific abnormalities that result in the condition. However, due to the number of causes of dwarfism, it may be impossible to determine definitively if a child will be born with dwarfism.

Dwarfism resulting from malnutrition or a hormonal abnormality may be treated with an appropriate diet or hormonal therapy. Growth hormone deficiency may be remedied via injections of Human Growth Hormone (HGH) during early life.


Genetic defects of most forms of dwarfism caused by bone dysplasia cannot be corrected, so therapeutic interventions are typically aimed at preventing or reducing pain or physical disability, increasing adult height, or mitigating psychosocial stresses and enhancing social adaptation.[6]

Forms of dwarfism associated with the endocrine system may be treated using hormonal therapy. If the cause is prepubescent hyposecretion of growth hormone, supplemental growth hormone may correct the abnormality. If the receptor for growth hormone is itself affected, the condition may prove harder to treat. Hypothyroidism is another possible cause of dwarfism that can be treated through hormonal therapy. Injections of thyroid hormone can mitigate the effects of the condition, but physical complications may be permanent.

Pain and disability may be ameliorated by physical therapy, braces or other orthotic devices, or by surgical procedures.[6] The only simple interventions that increase perceived adult height are dress enhancements, such as shoe lifts or hairstyle. Growth hormone is rarely used for shortness caused by bone dysplasias, since the height benefit is typically small (less than 5 cm [2 in]) and the cost high.[5] The most effective means of increasing adult height by several inches is distraction osteogenesis, though availability is limited and the cost is high in terms of money, discomfort, and disruption of life. Most people with dwarfism do not choose this option, and it remains controversial.[3] For other types of dwarfism, surgical treatment is not possible.

Society and culture

The Dwarf Don Sebastián de Morra, by Velázquez.


The appropriate term for describing a person of particularly short stature (or with the genetic condition achondroplasia) has historically been ambiguous, and has developed euphemistically over the past few centuries.

"Midget," whose etymology indicates a "small sandfly,"[24] came into prominence in the mid-1800s after Harriet Beecher Stowe used it in her novels Sunny Memories of Foreign Lands and Old Town Folks where she described children and an extremely short man, respectively.[4] Later most people of short stature considered the word to be offensive because it was the descriptive term applied to P. T. Barnum's dwarfs used for public amusement during the freak show era.[3] It is also not considered accurate as it is not a medical term or diagnosis, though it is sometimes used as a slang term to describe those who are particularly short, whether or not they have dwarfism.[25]

The first notable use of the term "dwarf" was by the Brothers Grimm in their fairy tale Snow White;[26] Jonathan Swift also used it in Gulliver's Travels to describe a giant who was only 20 ft tall compared to his 40 ft peers.[27] The plural form of "dwarf" for a person with dwarfism is "dwarfs", while "dwarves" describes the mythical creature. the word "dwarf" has also been condemned by some as not only inaccurate but also insensitive due to its mythical and fairy tale origins.[3]

The terms "dwarf", "little person", "LP", and "person of short stature" are now generally considered acceptable by most people affected by these disorders.[4]

Art and media depictions

Seneb, dwarf priest of funerary cults in 4th Dynasty (c. 2640-2510 BCE) Ancient Egypt, with his wife Senetites and their children.[28]

In art, literature, or movies, dwarfs are rarely depicted as "regular people who are very short" but rather as a species apart. Novelists, artists, and moviemakers may attach special moral or aesthetic significance to their "apartness" or misshapenness.

Artistic representations of dwarfism can be found on Greek vases and other ancient artifacts, including ancient Egyptian art in which dwarfs are likely to have been seen as a divine manifestation, with records indicating they could reach high positions in society.[29][30]

The Bhagavat Purana Hindu text devotes nine chapters to the adventures of Vamana, a dwarf avatar of Vishnu.

Depiction of dwarfs is also found in European paintings and many illustrations. Many European paintings (especially Spanish) of the 16th–19th centuries depict dwarfs by themselves or with others. In the Talmud, it is said that the second born son of the Egyptian Pharaoh of the Bible was a dwarf.[31] Recent scholarship has suggested that ancient Egyptians held dwarfs in high esteem.[32] Several important mythological figures of the North American Wyandot nation are portrayed as dwarfs.[33]

As popular media have become more widespread, the number of works depicting dwarfs has increased dramatically. Some feel that dwarf characters are often depicted based on the novelty factor of their stature rather than on other personal attributes. Dwarfism is depicted in many books, films, and TV series such as Austin Powers, Gulliver's Travels by Jonathan Swift[34], The Wizard of Oz, Willy Wonka and the Chocolate Factory, Little People Big World, Harry Potter, Seinfeld, In Bruges, The Tin Drum by Günter Grass, and the film The Station Agent.

See also


  1. ^ a b "MedlinePlus: Dwarfism". MedlinePlus. National Institute of Health. 2008-08-04. http://www.nlm.nih.gov/medlineplus/dwarfism.html. Retrieved 2008-10-03. 
  2. ^ a b c "Dwarfism". http://kidshealth.org/parent/growth/growth/dwarfism.html. Retrieved 2009-02-22. 
  3. ^ a b c d e f "Dwarfism Resources: Frequently Asked Questions". Little People of America. 2006-7-9. Archived from the original on 2007-07-12. http://web.archive.org/web/20060516011550/http://www.lpaonline.org/resources_faq.html. Retrieved 2006-11-14. 
  4. ^ a b c d Kennedy, Dan. "P.O.V. - Big Enough. What is Dwarfism?". Public Broadcasting Service. http://www.pbs.org/pov/pov2005/bigenough/special_dwarfism_ety.html. Retrieved 2008-11-18. 
  5. ^ a b Hagenäs L, Hertel T (2003). "Skeletal dysplasia, growth hormone treatment and body proportion: comparison with other syndromic and non-syndromic short children". Horm. Res. 60 Suppl 3: 65–70. doi:10.1159/000074504. PMID 14671400. http://content.karger.com/produktedb/produkte.asp?typ=fulltext&file=HRE2003060S03065. Retrieved 2008-11-17. 
  6. ^ a b c "Dwarfism: Treatment and drugs". MayoClinic.com. Mayo Foundation for Medical Education and Research. 2007-09-27. http://www.mayoclinic.com/health/dwarfism/DS01012/DSECTION=treatments-and-drugs. Retrieved 2008-11-18. 
  7. ^ University of Pennsylvania, Arts and Sciences: "The Effect of Adolescent Experience on Labor Market Outcomes: The Case of Height".
  8. ^ Science Blog: "Short children more likely to be bullied at school".
  9. ^ "Dwarfism and Dysplasias - Wheeless' Textbook of Orthopaedics". Wheeless' Textbook of Orthopaedics. Duke Orthopaedics. 2006-06. http://www.wheelessonline.com/ortho/dwarfism_and_dysplasias. Retrieved 2007-12-07. 
  10. ^ a b "Dwarfism: Symptoms". MayoClinic.com. Mayo Foundation for Medical Education and Research. http://www.mayoclinic.com/health/dwarfism/DS01012/DSECTION=symptoms. Retrieved 2009-01-29. 
  11. ^ "Dwarfism and Bone Dysplasias". Seattle Children's Hospital, Research & Foundation. http://orthopedics.seattlechildrens.org/conditions_treated/dwarfism_and_bone_dysplasias.asp. Retrieved 2008-11-18. 
  12. ^ a b "Dwarfism: Complications". MayoClinic.com. Mayo Foundation for Medical Education and Research. http://www.mayoclinic.com/health/dwarfism/DS01012/DSECTION=complications. Retrieved 2008-11-18. 
  13. ^ Escamilla RF, Hutchings JJ, Li CH, Forsham P (August 1966). "Achondroplastic dwarfism. Effects of treatment with human growth hormone". Calif Med 105 (2): 104–10. PMID 5946547. 
  14. ^ "The Pituitary Gland & Growth Disorders: An Overview". http://www.hormone.org/Growth/overview.cfm. Retrieved 2009-02-22. 
  15. ^ Hall, Judith A.; BETTY M. ADELSON (2005). Dwarfism: medical and psychosocial aspects of profound short stature. Baltimore: Johns Hopkins University Press. ISBN 0-8018-8121-8. 
  16. ^ a b Gollust SE, Thompson RE, Gooding HC, Biesecker BB (August 2003). "Living with achondroplasia in an average-sized world: an assessment of quality of life". American journal of medical genetics. Part A 120A (4): 447–58. doi:10.1002/ajmg.a.20127. PMID 12884421. 
  17. ^ "Achondroplasia - Genetics Home Reference". Genetics Home Reference. National Institute of Health. 2008-09-26. http://ghr.nlm.nih.gov/condition=achondroplasia. Retrieved 2008-10-01. 
  18. ^ "Growth Hormone Deficiency". UK Child Growth Foundation. http://www.childgrowthfoundation.org/ghd.htm. Retrieved 2009-01-16. 
  19. ^ "Causes of Dwarfism - WrongDiagnosis.com". http://www.wrongdiagnosis.com/d/dwarfism/causes.htm. Retrieved 2009-03-23. 
  20. ^ a b "DWARFISM (Algorithmic Diagnosis of Symptoms and Signs) - WrongDiagnosis.com". http://www.wrongdiagnosis.com/d/dwarfism/book-diseases-1a.htm. Retrieved 2009-02-22. 
  21. ^ "Dwarfism: Tests and diagnosis". Mayo Clinic. Mayo Foundation for Medical Education and Research. 2007-08-27. http://www.mayoclinic.com/health/dwarfism/DS01012/DSECTION=tests-and-diagnosis. Retrieved 2008-11-18. 
  22. ^ Kemp, Stephen (2008-09-15). "eMedicine - Growth Hormone Deficiency : Article by Stephen Kemp". eMedicine. WebMD, Inc.. http://www.emedicine.com/PED/topic1810.htm. Retrieved 2008-11-18. 
  23. ^ "Short Stature in Children". eMedicineHealth.com. WebMD, Inc.. http://www.emedicinehealth.com/short_stature_in_children/article_em.htm. Retrieved 2008-11-18. 
  24. ^ "midget". Online Etymology Dictionary. Dictionary.com. http://dictionary.reference.com/browse/midget. Retrieved 2008-11-18. 
  25. ^ "Midget definition". MedicineNet. MedicineNet, Inc.. 3/9/2003. http://www.medterms.com/script/main/art.asp?articlekey=22596. Retrieved 2008-11-18. 
  26. ^ Grimm, Jacob and Wilhelm. Snow White. The Harvard Classics. http://www.bartleby.com/17/2/25.html. 
  27. ^ Swift, Jonathan (1919). Gulliver's Travels. Harrap. http://books.google.com/books?id=IE5bAAAAMAAJ. 
  28. ^ "Ancient Egypt:Kingdom of the Pharaohs", R. Hamilton, p. 47, Paragon, 2006, ISBN 1-40548-288-5
  29. ^ "Ancient Egyptian Medicine",John F. Nunn, University of Oklahoma Press, 2002, p. 78-79, ISBN 0806135042
  30. ^ Dwarfs Commanded Respect In Ancient Egypt, ScienceDaily, 27 Dec 2005
  31. ^ The Talmud - Chapter Vi. Death Of Jacob And His Sons--Moses--The Deliverance From Egypt. URL accessed April 23, 2007.
  32. ^ Kozma, Chahira (2005-12-27). "Dwarfs in ancient Egypt". American Journal of Medical Genetics 140A (4): 303–311. doi:10.1002/ajmg.a.31068. http://www3.interscience.wiley.com/journal/112222883/abstract. Retrieved 2008-11-12. 
  33. ^ Trigger, Bruce G., The Children of Aataentsic: A History of the Huron People to 1660 McGill-Queen's University Press, 1987 ISBN 0-7735-0627-6, p. 529.
  34. ^ Gulliver's Travels: Complete, Authoritative Text with Biographical and Historical Contexts, Palgrave Macmillan 1995 (p. 21). The quote has been misattributed to Alexander Pope, who wrote to Swift in praise of the book just a day earlier.

External links

Simple English

Dwarfism is used to describe a person of short stature, less than 4 feet 10 inches (147 cm). This can occur naturally, but often it is a medical condition. Dwarfism is often caused by the person inheriting an allele (mutant gene), which produces a defect in development. Defects caused by genetics are called congenital defects, and usually cannot be cured.

The most common cause of dwarfism is a defect in bone development called Achondroplasia, in which the limbs are short in proportion to the body. This accounts for 70% of cases. Extreme shortness, with body parts of normal proportions, may be caused by growth hormone deficiency, once known as pituitary dwarfism.[1]

There are more than 200 other conditions which may cause dwarfism.[2]


  1. Kennedy, Dan. "P.O.V. - Big Enough. What is Dwarfism?". Public Broadcasting Service. http://www.pbs.org/pov/pov2005/bigenough/special_dwarfism_ety.html. Retrieved 2008-11-18. 
  2. "MedlinePlus: Dwarfism". MedlinePlus. National Institute of Health. 2008-08-04. http://www.nlm.nih.gov/medlineplus/dwarfism.html. Retrieved 2008-10-03. 


Got something to say? Make a comment.
Your name
Your email address