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EA-3834: Wikis

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EA-3834
Systematic (IUPAC) name
(1-methylpiperidin-4-yl) 2-hydroxy-3-methyl-2-phenylbutanoate
Identifiers
CAS number  ?
ATC code  ?
PubChem 21150216
Chemical data
Formula C 17H25NO3  
Mol. mass 291.384 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

EA-3834 is a potent anticholinergic deliriant drug with a fairly long duration of action, related to the chemical warfare agent 3-Quinuclidinyl benzilate (QNB). It was developed under contract to Edgewood Arsenal during the 1960s as part of the US military chemical weapons program, during research to improve upon the properties of earlier agents such as QNB.

EA-3834 has a potency and central to peripheral effects ratio only slightly less than that of related compounds such as EA-3443, and is faster acting and shorter lasting, although not as much as other compounds such as 302196.[1][2]

See also

References

  1. ^ Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents, Volume 1 (1982). Commission on Life Sciences. The National Academies Press. pp200-204.
  2. ^ Ketchum JS. Chemical Warfare Secrets Almost Forgotton. A Personal Story of Medical Testing of Army Volunteers with Incapacitating Chemical Agents During the Cold War. ChemBooks Inc 2006. ISBN 978-1-4243-0080-8
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