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Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor)
Identifiers
Symbols EBI2;
External IDs OMIM605741 MGI2442034 HomoloGene28066 IUPHAR: GeneCards: EBI2 Gene
RNA expression pattern
PBB GE EBI2 205419 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 1880 321019
Ensembl ENSG00000169508 ENSMUSG00000051212
UniProt P32249 n/a
RefSeq (mRNA) NM_004951 NM_183031
RefSeq (protein) NP_004942 NP_898852
Location (UCSC) Chr 13:
98.74 - 98.76 Mb
Chr 14:
121.09 - 121.1 Mb
PubMed search [1] [2]

G-protein coupled receptor 183 is a protein that in humans is encoded by the GPR183 gene.[1][2]

This gene was identified by the up-regulation of its expression upon Epstein-Barr virus infection of primary B lymphocytes. This gene is predicted to encode a G protein-coupled receptor that is most closely related to the thrombin receptor. Expression of this gene was detected in B-lymphocyte cell lines and lymphoid tissues but not in T-lymphocyte cell lines or peripheral blood T lymphocytes. The function of this gene is unknown.[2]

References

Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.  
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Rosenkilde MM, Benned-Jensen T, Andersen H, et al. (2006). "Molecular pharmacological phenotyping of EBI2. An orphan seven-transmembrane receptor with constitutive activity.". J. Biol. Chem. 281 (19): 13199–208. doi:10.1074/jbc.M602245200. PMID 16540462.  

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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