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Eukaryotic translation initiation factor 1

PDB rendering based on 2if1.
Available structures
Symbols EIF1; EIF1A; A121; EIF-1; ISO1; SUI1
External IDs MGI3643981 HomoloGene48375 GeneCards: EIF1 Gene
Species Human Mouse
Entrez 10209 620480
Ensembl ENSG00000173812 ENSMUSG00000068629
UniProt P41567 n/a
RefSeq (mRNA) NM_005801 XM_884867
RefSeq (protein) NP_005792 XP_889960
Location (UCSC) Chr 17:
37.1 - 37.1 Mb
Chr 7:
84.71 - 84.71 Mb
PubMed search [1] [2]

Eukaryotic translation initiation factor 1 is a protein that in humans is encoded by the EIF1 gene.[1][2][3]


  1. ^ Fields C, Adams MD (Feb 1994). "Expressed sequence tags identify a human isolog of the suil translation initiation factor". Biochem Biophys Res Commun 198 (1): 288-91. doi:10.1006/bbrc.1994.1040. PMID 7904817.  
  2. ^ Sheikh MS, Fernandez-Salas E, Yu M, Hussain A, Dinman JD, Peltz SW, Huang Y, Fornace AJ Jr (Jul 1999). "Cloning and characterization of a human genotoxic and endoplasmic reticulum stress-inducible cDNA that encodes translation initiation factor 1(eIF1(A121/SUI1))". J Biol Chem 274 (23): 16487-93. PMID 10347211.  
  3. ^ "Entrez Gene: EIF1 eukaryotic translation initiation factor 1".  

External links

Further reading

  • Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags.". Genome Res. 6 (9): 807–28. doi:10.1101/gr.6.9.807. PMID 8889549.  
  • Lian Z, Pan J, Liu J, et al. (1999). "The translation initiation factor, hu-Sui1 may be a target of hepatitis B X antigen in hepatocarcinogenesis.". Oncogene 18 (9): 1677–87. doi:10.1038/sj.onc.1202470. PMID 10208429.  
  • Fletcher CM, Pestova TV, Hellen CU, Wagner G (1999). "Structure and interactions of the translation initiation factor eIF1.". EMBO J. 18 (9): 2631–7. doi:10.1093/emboj/18.9.2631. PMID 10228174.  
  • Chin LS, Singh SK, Wang Q, Murray SF (2000). "Identification of okadaic-acid-induced genes by mRNA differential display in glioma cells.". J. Biomed. Sci. 7 (2): 152–9. doi:10.1007/BF02256622. PMID 10754390.  
  • Mendell JT, Medghalchi SM, Lake RG, et al. (2000). "Novel Upf2p orthologues suggest a functional link between translation initiation and nonsense surveillance complexes.". Mol. Cell. Biol. 20 (23): 8944–57. doi:10.1128/MCB.20.23.8944-8957.2000. PMID 11073994.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Rush J, Moritz A, Lee KA, et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.". Nat. Biotechnol. 23 (1): 94–101. doi:10.1038/nbt1046. PMID 15592455.  


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