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ENTPD1: Wikis


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From Wikipedia, the free encyclopedia

Ectonucleoside triphosphate diphosphohydrolase 1
Symbols ENTPD1; ATPDase; CD39; NTPDase-1
External IDs OMIM601752 MGI102805 HomoloGene20423 GeneCards: ENTPD1 Gene
RNA expression pattern
PBB GE ENTPD1 209473 at tn.png
PBB GE ENTPD1 207691 x at tn.png
PBB GE ENTPD1 209474 s at tn.png
More reference expression data
Species Human Mouse
Entrez 953 12495
Ensembl ENSG00000138185 ENSMUSG00000048120
UniProt P49961 Q544U5
RefSeq (mRNA) NM_001776 NM_009848
RefSeq (protein) NP_001767 NP_033978
Location (UCSC) Chr 10:
97.46 - 97.62 Mb
Chr 19:
40.76 - 40.79 Mb
PubMed search [1] [2]

Ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1) also known as CD39 (Cluster of Differentiation 39), is a human gene.[1]



See also

Further reading

  • Maliszewski CR, Delespesse GJ, Schoenborn MA, et al. (1994). "The CD39 lymphoid cell activation antigen. Molecular cloning and structural characterization.". J. Immunol. 153 (8): 3574–83. PMID 7930580.  
  • Christoforidis S, Papamarcaki T, Galaris D, et al. (1996). "Purification and properties of human placental ATP diphosphohydrolase.". Eur. J. Biochem. 234 (1): 66–74. doi:10.1111/j.1432-1033.1995.066_c.x. PMID 8529670.  
  • Wang TF, Guidotti G (1996). "CD39 is an ecto-(Ca2+,Mg2+)-apyrase.". J. Biol. Chem. 271 (17): 9898–901. doi:10.1074/jbc.271.17.9898. PMID 8626624.  
  • Kaczmarek E, Koziak K, Sévigny J, et al. (1997). "Identification and characterization of CD39/vascular ATP diphosphohydrolase.". J. Biol. Chem. 271 (51): 33116–22. doi:10.1074/jbc.271.51.33116. PMID 8955160.  
  • Robson SC, Kaczmarek E, Siegel JB, et al. (1997). "Loss of ATP diphosphohydrolase activity with endothelial cell activation.". J. Exp. Med. 185 (1): 153–63. doi:10.1084/jem.185.1.153. PMID 8996251.  
  • Gray IC, Fallowfield J, Ford S, et al. (1997). "An integrated physical and genetic map spanning chromosome band 10q24.". Genomics 43 (1): 85–8. doi:10.1006/geno.1997.4809. PMID 9226376.  
  • Makita K, Shimoyama T, Sakurai Y, et al. (1999). "Placental ecto-ATP diphosphohydrolase: its structural feature distinct from CD39, localization and inhibition on shear-induced platelet aggregation.". Int. J. Hematol. 68 (3): 297–310. doi:10.1016/S0925-5710(98)00080-2. PMID 9846014.  
  • Matsumoto M, Sakurai Y, Kokubo T, et al. (1999). "The cDNA cloning of human placental ecto-ATP diphosphohydrolases I and II.". FEBS Lett. 453 (3): 335–40. doi:10.1016/S0014-5793(99)00751-6. PMID 10405171.  
  • Kittel A, Kaczmarek E, Sevigny J, et al. (1999). "CD39 as a caveolar-associated ectonucleotidase.". Biochem. Biophys. Res. Commun. 262 (3): 596–9. doi:10.1006/bbrc.1999.1254. PMID 10471369.  
  • Koziak K, Kaczmarek E, Kittel A, et al. (2000). "Palmitoylation targets CD39/endothelial ATP diphosphohydrolase to caveolae.". J. Biol. Chem. 275 (3): 2057–62. doi:10.1074/jbc.275.3.2057. PMID 10636909.  
  • Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. doi:10.1073/pnas.97.7.3491. PMID 10737800.  
  • Goepfert C, Imai M, Brouard S, et al. (2001). "CD39 modulates endothelial cell activation and apoptosis.". Mol. Med. 6 (7): 591–603. PMID 10997340.  
  • Adrian K, Bernhard MK, Breitinger HG, Ogilvie A (2000). "Expression of purinergic receptors (ionotropic P2X1-7 and metabotropic P2Y1-11) during myeloid differentiation of HL60 cells.". Biochim. Biophys. Acta 1492 (1): 127–38. PMID 11004484.  
  • Kittel A, Garrido M, Varga G (2002). "Localization of NTPDase1/CD39 in normal and transformed human pancreas.". J. Histochem. Cytochem. 50 (4): 549–56. PMID 11897808.  
  • Kaneider NC, Egger P, Dunzendorfer S, et al. (2002). "Reversal of thrombin-induced deactivation of CD39/ATPDase in endothelial cells by HMG-CoA reductase inhibition: effects on Rho-GTPase and adenosine nucleotide metabolism.". Arterioscler. Thromb. Vasc. Biol. 22 (6): 894–900. doi:10.1161/01.ATV.0000018305.95943.F7. PMID 12067895.  
  • Drosopoulos JH (2002). "Roles of Asp54 and Asp213 in Ca2+ utilization by soluble human CD39/ecto-nucleotidase.". Arch. Biochem. Biophys. 406 (1): 85–95. doi:10.1016/S0003-9861(02)00414-9. PMID 12234494.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Krötz F, Sohn HY, Keller M, et al. (2002). "Depolarization of endothelial cells enhances platelet aggregation through oxidative inactivation of endothelial NTPDase.". Arterioscler. Thromb. Vasc. Biol. 22 (12): 2003–9. doi:10.1161/01.ATV.0000043454.08172.51. PMID 12482826.  
  • Rossatto ER, da Silva LB, Pereira GS, et al. (2003). "ATP diphosphohydrolase in human platelets from patients with coronary arteries heart disease.". Platelets 14 (1): 47–52. doi:10.1080/0953710021000062923. PMID 12623446.  
  • Sørensen CE, Amstrup J, Rasmussen HN, et al. (2004). "Rat pancreas secretes particulate ecto-nucleotidase CD39.". J. Physiol. (Lond.) 551 (Pt 3): 881–92. doi:10.1113/jphysiol.2003.049411. PMID 12832497.  

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