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ETV1: Wikis


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From Wikipedia, the free encyclopedia

Ets variant gene 1
Symbols ETV1; DKFZp781L0674; ER81; MGC104699; MGC120533; MGC120534
External IDs OMIM600541 MGI99254 HomoloGene3636 GeneCards: ETV1 Gene
RNA expression pattern
PBB GE ETV1 217061 s at tn.png
PBB GE ETV1 206501 x at tn.png
PBB GE ETV1 217053 x at tn.png
More reference expression data
Species Human Mouse
Entrez 2115 14009
Ensembl ENSG00000006468 ENSMUSG00000004151
UniProt P50549 Q549J8
RefSeq (mRNA) NM_004956 NM_007960
RefSeq (protein) NP_004947 NP_031986
Location (UCSC) Chr 7:
13.9 - 14 Mb
Chr 12:
39.29 - 39.38 Mb
PubMed search [1] [2]

ETS translocation variant 1 is a protein that in humans is encoded by the ETV1 gene.[1][2]


  1. ^ Brown TA, McKnight SL (Dec 1993). "Specificities of protein-protein and protein-DNA interaction of GABP alpha and two newly defined ets-related proteins". Genes Dev 6 (12B): 2502-12. PMID 1340465.  
  2. ^ "Entrez Gene: ETV1 ets variant gene 1".  

Further reading

  • Monté D, Coutte L, Baert JL, et al. (1995). "Molecular characterization of the ets-related human transcription factor ER81.". Oncogene 11 (4): 771–9. PMID 7651741.  
  • Jeon IS, Davis JN, Braun BS, et al. (1995). "A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1.". Oncogene 10 (6): 1229–34. PMID 7700648.  
  • Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction.". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.  
  • Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing.". Genome Res. 7 (4): 353–8. PMID 9110174.  
  • Carrère S, Verger A, Flourens A, et al. (1998). "Erg proteins, transcription factors of the Ets family, form homo, heterodimers and ternary complexes via two distinct domains.". Oncogene 16 (25): 3261–8. doi:10.1038/sj.onc.1201868. PMID 9681824.  
  • Coutte L, Monté D, Imai K, et al. (2000). "Characterization of the human and mouse ETV1/ER81 transcription factor genes: role of the two alternatively spliced isoforms in the human.". Oncogene 18 (46): 6278–86. doi:10.1038/sj.onc.1203020. PMID 10597226.  
  • Janknecht R (2001). "Cell type-specific inhibition of the ETS transcription factor ER81 by mitogen-activated protein kinase-activated protein kinase 2.". J. Biol. Chem. 276 (45): 41856–61. doi:10.1074/jbc.M106630200. PMID 11551945.  
  • Wu J, Janknecht R (2003). "Regulation of the ETS transcription factor ER81 by the 90-kDa ribosomal S6 kinase 1 and protein kinase A.". J. Biol. Chem. 277 (45): 42669–79. doi:10.1074/jbc.M205501200. PMID 12213813.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Janknecht R (2003). "Regulation of the ER81 transcription factor and its coactivators by mitogen- and stress-activated protein kinase 1 (MSK1).". Oncogene 22 (5): 746–55. doi:10.1038/sj.onc.1206185. PMID 12569367.  
  • Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science 300 (5620): 767–72. doi:10.1126/science.1083423. PMID 12690205.  
  • Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.  
  • Goel A, Janknecht R (2003). "Acetylation-mediated transcriptional activation of the ETS protein ER81 by p300, P/CAF, and HER2/Neu.". Mol. Cell. Biol. 23 (17): 6243–54. doi:10.1128/MCB.23.17.6243-6254.2003. PMID 12917345.  
  • Dowdy SC, Mariani A, Janknecht R (2004). "HER2/Neu- and TAK1-mediated up-regulation of the transforming growth factor beta inhibitor Smad7 via the ETS protein ER81.". J. Biol. Chem. 278 (45): 44377–84. doi:10.1074/jbc.M307202200. PMID 12947087.  
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.  
  • Goel A, Janknecht R (2004). "Concerted activation of ETS protein ER81 by p160 coactivators, the acetyltransferase p300 and the receptor tyrosine kinase HER2/Neu.". J. Biol. Chem. 279 (15): 14909–16. doi:10.1074/jbc.M400036200. PMID 14747462.  
  • Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Gocke CB, Yu H, Kang J (2005). "Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates.". J. Biol. Chem. 280 (6): 5004–12. doi:10.1074/jbc.M411718200. PMID 15561718.  

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