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Earl Wilbur Sutherland, Jr.
Born November 19, 1915
Burlingame, Kansas
Died March 9, 1974
Miami, Florida
Nationality American
Fields biochemistry
Institutions Case Western Reserve University Vanderbilt University
Alma mater Washburn University
Known for epinephrine, cyclic AMP
Influences Carl Cori, Gerty Cori
Notable awards Nobel Prize in Physiology or Medicine in 1971

Earl Wilbur Sutherland Jr. (November 19, 1915 – March 9, 1974) was an American pharmacologist and biochemist. Sutherland was born in Burlingame, Kansas. He won a Nobel Prize in Physiology or Medicine in 1971 "for his discoveries concerning the mechanisms of the action of hormones," especially epinephrine, via second messengers (such as cyclic adenosine monophosphate, cyclic AMP).



Sutherland received his bachelor's degree in chemistry in 1937 from Washburn University, Topeka, Kansas and earned his medical degree in 1942 from Washington University School of Medicine in St. Louis. After serving as a doctor in World War II, he returned to Washington University as a researcher in the pharmacology laboratory of Nobel laureate Carl Ferdinand Cori. In 1953, he became director of the department of pharmacology at Case Western Reserve University (then Western Reserve University) in Cleveland, Ohio, where he discovered the role of cyclic AMP in mediating the action of certain hormones. In 1963, desiring to limit his duties to research, Sutherland moved to Vanderbilt University School of Medicine in Nashville, where he was a professor of physiology until 1973. At the time of his death in 1974, Sutherland was a distinguished professor of biochemistry at University of Miami Medical School.

Awards and honours

In addition to the Nobel Prize of 1971, Sutherland won the Albert Lasker Award for basic medical research in 1970, and received the National Medal of Science in 1973. He was elected to the National Academy of Sciences in 1966. A residential dormitory at Vanderbilt was named in Sutherland's honor, and a plaque and photographic display there commemorate his achievements.

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