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Echinopsidine
Systematic (IUPAC) name
1-methyl-2,3-dihydroquinolin-4-imine hydroiodide
Identifiers
CAS number 58916-73-7
ATC code none
PubChem 161461
ChemSpider 141825
Chemical data
Formula C10H13IN2 
Mol. mass 288.13 g/mol
Synonyms Echinopsidine Iodide
Therapeutic considerations
Pregnancy cat.  ?
Legal status Prescription only
Routes Oral

Echinopsidine (Adepren) is an antidepressant used in Bulgaria for the treatment of depression.[1][2] It increases serotonin, norepinephrine, and dopamine levels in the brain and is believed to act as a monoamine oxidase inhibitor (MAOI).[3][4][5] Echinopsidine is found naturally in Echinops echinatus along with the related alkaloids echinopsine and echinozolinone.[6]

See also

References

  1. ^ Guliamov MG (1982). "[Experience with the use of new Bulgarian psychotropic drugs]" (in Russian). Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952) 82 (11): 115–22. PMID 6758442. 
  2. ^ Guliamov MG (1986). "[Comparative evaluation of the therapeutic efficacy of the antidepressants adepren, linamiphen and emovit]" (in Russian). Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952) 86 (4): 582–7. PMID 3716711. 
  3. ^ Tiutiulkova N, Gorancheva Iu (1978). "[Effect of adepren on the cerebral concentration of serotonin]" (in Bulgarian). Eksperimentalna Meditsina I Morfologiia 17 (2): 83–5. PMID 658004. 
  4. ^ Stefanova D, Tiutiulkova N, Nikolova M (1976). "[Effect of adepren on the behavior and brain catecholamines of rats in an open field setup]" (in Bulgarian). Eksperimentalna Meditsina I Morfologiia 15 (1): 42–6. PMID 1269462. 
  5. ^ Tiutiulkova NI, Gorancheva IuI (1975). "[Excretion of dopamine, noradrenaline, adrenaline, vanilmandelic acid and 5-hydroxyindoleacetic acid in the urine of volunteers treated with adepren]" (in Bulgarian). Eksperimentalna Meditsina I Morfologiia 14 (4): 187–9. PMID 1222713. 
  6. ^ Indian Medicinal Plants An Illustrated Dictionary. Springer-Verlag Berlin Heidelberg. 2007. ISBN 0-387-70637-2. http://books.google.com/books?id=gMwLwbUwtfkC&lpg=PA230&dq=Echinopsidine&as_brr=3&pg=PA230#v=onepage&q=&f=false. 







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