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Efungumab: Wikis


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Efungumab ?
Monoclonal antibody
Source Human
Target Fungal Hsp90
CAS number  ?
ATC code none
PubChem  ?
Chemical data
Formula  ?
Mol. mass Approximately 27.2 kDa
Pharmacokinetic data
Bioavailability Not applicable (IV only)
Protein binding High
Metabolism  ?
Half life 1–2 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes Intravenous

Efungumab (trade name Mycograb) is a human monoclonal antibody developed by NeuTec Pharma (a subsidiary of Novartis), intended to treat invasive Candida infection in combination with amphotericin B. The European Medicines Agency has twice refused to grant marketing authorization for Mycograb, citing product safety and quality issues.[1]


  1. ^ European Medicines Agency (2007). REFUSAL CHMP ASSESSMENT REPORT FOR MYCOGRAB. Procedure No. EMEA/H/C/658PDF (370 KiB). London: European Medicines Agency. Retrieved on 2007-11-20. Detailed assessment report with comprehensive overview of reasons for refusal of marketing authorization.


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