The Full Wiki

More info on End-diastolic volume

End-diastolic volume: Wikis

Advertisements
  

Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.

Encyclopedia

From Wikipedia, the free encyclopedia

In cardiovascular physiology, end-diastolic volume (EDV) is the volume of blood in a ventricle at the end of filling (diastole). Because greater EDVs cause greater distention of the ventricle, EDV is often used synonymously with preload, which refers to the length of the sarcomeres in cardiac muscle prior to contraction (systole). An increase in EDV increases the preload on the heart and, through the Frank-Starling mechanism of the heart, increases the amount of blood ejected from the ventricle during systole (stroke volume).

Parameters affecting EDV

Because nearly two-thirds of the blood in the systemic circulation is stored in the venous system, end-diastolic volume is closely related to venous compliance.

  • Increasing venous compliance elevates the capacitance of the veins, reducing venous return and therefore end-diastolic volume.
  • Decreasing venous compliance has the opposite effect. For example, activation of the baroreceptor reflex (occurring, for instance, in acute hemorrhage) causes venoconstriction, which decreases venous compliance, improves venous return, and therefore increases end-diastolic volume.

Sample values

Parameter Value
end-diastolic volume (EDV) 120 ml
end-systolic volume (ESV) 50 ml
stroke volume (SV) 70 ml
ejection fraction (Ef) 58%
heart rate (HR) 70 bpm
cardiac output (CO) 4.9 L/m

See also

Advertisements

Advertisements






Got something to say? Make a comment.
Your name
Your email address
Message