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Transverse section of human tibial nerve.
Illu nerve structure.jpg
Nerve structure
Gray's subject #183 728
MeSH Endoneurium

The endoneurium is a layer of delicate connective tissue that encloses the myelin sheath of a nerve fiber within a fasciculus.[1]

It is continuous with septa which pass inward from the innermost layer of the perineurium, and shows a ground substance in which are imbedded fine bundles of fibrous connective tissue, primarily collagen, running for the most part longitudinally.

It serves to support capillary vessels, arranged so as to form a net-work with elongated meshes.

It is found in other places too, such as surrounding the Schwann cells on the peripheral side of the transitional zone on the auditory nerve.[2]


  1. ^ Elaine N. Marieb and Katja Hoehn (2007). Human Anatomy & Physiology (7th Ed.). Pearson. pp. 498–9. ISBN 0-805-35909-5.  
  2. ^ Fraher JP (2000). "The transitional zone and CNS regeneration". J. Anat. 196 (Pt 1): 137–58. PMID 10697296.  

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