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Enprostil
Systematic (IUPAC) name
Methyl 7-[(1S,2S,3S)- 3-hydroxy-2-[(S,E)-3-hydroxy-4-phenoxybut-1-enyl]-5-oxocyclopentyl]hepta-4,5-dienoate
Identifiers
CAS number 73121-56-9
ATC code A02BB02
PubChem 51744
Chemical data
Formula C 23H28O6  
Mol. mass 400.46 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Enprostil is a synthetic prostaglandin designed to resemble dinoprostone.

It is classified by the World Health Organization under "A02B: Drugs for peptic ulcer and gastro-oesophageal reflux disease."

External links

  • Toshina K, Hirata I, Maemura K, Sasaki S, Murano M, Nitta M, Yamauchi H, Nishikawa T, Hamamoto N, Katsu K (2000). "Enprostil, a prostaglandin-E(2) analogue, inhibits interleukin-8 production of human colonic epithelial cell lines.". Scand J Immunol 52 (6): 570–5. doi:10.1046/j.1365-3083.2000.00815.x. PMID 11119262.  
  • Tari A, Hamada M, Kamiyasu T, Sumii K, Haruma K, Inoue M, Kishimoto S, Kajiyama G, Walsh J (1997). "Effect of enprostil on omeprazole-induced hypergastrinemia and inhibition of gastric acid secretion in peptic ulcer patients.". Dig Dis Sci 42 (8): 1741–6. doi:10.1023/A:1018825902055. PMID 9286243.  
  • Ching C, Lam S (1995). "A comparison of two prostaglandin analogues (enprostil vs misoprostol) in the treatment of acute duodenal ulcer disease.". J Gastroenterol 30 (5): 607–14. doi:10.1007/BF02367786. PMID 8574332.  
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