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Epithelioid cell: Wikis

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Epithelioid histiocytes (Epithelioid cells) are activated macrophages resembling epithelial cells: [1] elongated, with finely granular, pale eosinophilic (pink) cytoplasm and central, ovoid nucleus(oval or elongate), which is less dense than that of a lymphocyte. They have indistinct shape contour, often appear to merge into one another and form aggregates.

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Clinical significance

The presence of epithelioid histiocytes may characterise some pathologic conditions, mainly granulomatous inflammation, including Orofacial granulomatosis[2]. The excessive proliferation of them on skin causes reticulohistiocytoma and somewhat it is associated with arthritis.

See also

References

  1. ^ "Dorlands Medical Dictionary:epithelioid cell". http://www.mercksource.com/pp/us/cns/cns_hl_dorlands_split.jsp?pg=/ppdocs/us/common/dorlands/dorland/two/000018652.htm.  
  2. ^ Bogenrieder T, Rogler G, Vogt T, Landthaler M, Stolz W (2003). "Orofacial granulomatosis as the initial presentation of Crohn's disease in an adolescent". Dermatology (Basel) 206 (3): 273–8. doi:10.1159/000068900. PMID 12673090.  

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