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Epratuzumab: Wikis

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Epratuzumab ?
Monoclonal antibody
Type whole antibody
Source humanized (from mouse)
Target CD22
Identifiers
CAS number 205923-57-5
ATC code none
Chemical data
Formula  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status

Epratuzumab is a humanized monoclonal antibody. Potential uses may be found in oncology and in treatment of inflammatory autoimmune disorders, such as lupus (SLE).[1][2] The manufacturers in August 2009 announced success in early trials against SLE.[3]

Mechanism

Epratuzumab binds to the glycoprotein CD22 of mature and malignant B-cells, which it destroys by antibody-dependent cell-mediated cytotoxicity.[4]

See also

External links

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