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Ethylamphetamine
Systematic (IUPAC) name
N-ethyl-1-phenyl-propan-2-amine
Identifiers
CAS number 457-87-4
ATC code A08AA06
PubChem 9982
Chemical data
Formula C 11H17N 
Mol. mass 163.259 g/mol
Synonyms N-ethylamphetamine
Pharmacokinetic data
Bioavailability  ?
Metabolism Hepatic
Half life  ?
Excretion Renal
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes Oral, Sublingual, Insufflated (Snorted), Inhaled (Vaporized), Intravenous, Rectal

Ethylamphetamine (Apetinil, Adiparthrol), also known as etilamfetamine or N-ethylamphetamine, is a stimulant drug of the phenethylamine and amphetamine chemical classes. It was invented in the early 1900s and was subsequently used as an anorectic or appetite suppressant in the 1950s,[1] but was not as commonly used as other amphetamines such as amphetamine, methamphetamine, and benzphetamine, and was largely discontinued once newer drugs such as phenmetrazine were introduced.

Contents

Molecular structure

The molecular structure of ethylamphetamine is analogous to amphetamine's.[Note 1] It is a substituted amphetamine, with an ethyl group on the amphetamine backbone.[Note 2][Note 3]

Recreational use

Ethylamphetamine can be used as a recreational drug and, while its prevalence is less than amphetamine's, it is still encountered as a substance taken for recreational purposes.

Ethylamphetamine produces effects similar to amphetamine and methamphetamine, its potency being slightly greater than amphetamine's and lesser than methamphetamine's.[Note 4]

Dosage for recreational use of ethylamphetamine is typically 10-30 milligrams but can vary with a person's level of tolerance, metabolism and weight. In general, the dosage for ethylamphetamine is similar to that for racemic amphetamine; however, a slightly lower dose is used for ethylamphetamine because of its higher potency.

See also

Notes

  1. ^ Amphetamine is a substituted phenethylamine with a methyl group at RA position.
  2. ^ The ethyl group of ethylamphetamine is at RN position, hence the name N-ethylamphetamine.
  3. ^ Ethylamphetamine is structurally similar to N-methylamphetamine (methamphetamine), the ethyl group being replaced in methamphetamine with a methyl group.
  4. ^ Ethylamphetamine's higher potency may make its risk of causing abuse, dependence and/or addiction greater compared to amphetamine.

References

  1. ^ Junet R. Ethylamphetamine in the treatment of obesity. Praxis. 1956 Oct 25;45(43):986-8. (French)







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