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Eticyclidine
Systematic (IUPAC) name
N-ethyl-1-phenylcyclohexylamine
Identifiers
CAS number 2201-15-2
ATC code none
PubChem 16622
Chemical data
Formula C 14H21N 
Mol. mass 203.323 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status Schedule I / Class A
Routes  ?

Eticyclidine (PCE, CI-400) is a dissociative anesthetic drug with hallucinogenic effects. It is similar in effects to phencyclidine but is slightly more potent. PCE was developed by Parke-Davis in the 1970s and evaluated for anesthetic potential under the code name CI-400,[1] but research into PCE was not continued after the development of ketamine, a similar drug with more favourable properties.[2] PCE is slightly more potent than PCP and has similar effects, but its unpleasant taste and tendency to cause nausea made it less accepted by users.[3] Due to its similarity in effects to PCP, PCE was placed into the Schedule 1 list of illegal drugs in the 1970s, although it was only briefly abused in the 1970s and 1980s and is now little known.

See also

References

  1. ^ LEVY L, CAMERON DE, AITKEN RC (March 1960). "Observation on two psychotomimetic drugs of piperidine derivation--CI 395 (sernyl) and CI 400". The American Journal of Psychiatry 116: 843–4. PMID 14416411.  
  2. ^ Kalir A, Edery H, Pelah Z, Balderman D, Porath G. 1-Phenylcycloalkylamine derivatives. II. Synthesis and pharmacological activity. Journal of Medicinal Chemistry. 1969. 12(3):473-477
  3. ^ Structure Activity of PCP analogs







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