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Etoxeridine: Wikis

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Etoxeridine
Systematic (IUPAC) name
ethyl 1-[2-(2-hydroxyethoxy)ethyl]-4-phenylpiperidine-4-carboxylate
Identifiers
CAS number 469-82-9
ATC code none
PubChem 61122
Chemical data
Formula C18H27NO4 
Mol. mass 321.41 g/mol
SMILES eMolecules & PubChem
Synonyms Etoxeridine, Carbetidine, Atenos
Therapeutic considerations
Pregnancy cat.  ?
Legal status  ? (UK) Schedule I (US)

Etoxeridine (Carbetidine, Atenos) is a 4-phenylpiperidine derivative that is related to the opioid analgesic drug pethidine (meperidine).

Etoxeridine was developed in the 1950s and investigated for use in surgical anesthesia, however it was never commercialised and is not currently used in medicine.[1][2][3]

References

  1. ^ Merlevede E, Levis S. Pharmacological study of carbetidine, a new synthetic analgesic. (French). Archives Internationales de Pharmacodynamie et de Therapie. 1958 May 1;115(1-2):213-32.
  2. ^ Sironi PG. Brief note on a new synthetic analgesic: carbetidine hydrochloride. (Italian). Minerva Anestesiologica. 1959 Jun;25(6):251-4.
  3. ^ Crawford JS, Foldes FF. Studies on the respiratory and circulatory effects of carbetidine HCI used for supplementation of thiopentone sodium-nitrous oxide-oxygen anaesthesia. British Journal of Anaesthesia. 1959 Aug;31:348-51.
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