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Systematic (IUPAC) name
CAS number 522-11-2
ATC code none
PubChem 73416
Chemical data
Formula C11H12O2 
Mol. mass 347.362 g/mol
SMILES eMolecules & PubChem
Therapeutic considerations
Pregnancy cat.  ?
Legal status Legal

Evoxine (Haploperine) is an alkaloid with hypnotic and sedative effects. It is found naturally in a variety of Australian and African plants including Evodia xanthoxyloides[1] and Teclea gerrardii.[2]


  1. ^ Eastwood FW, Hughes GK, Ritchie E. Alkaloids of the Australian Rutaceae: Evodia xanthoxyloides F.Muell. IV. The structures of Evoxine and Evoxoidine. Australian Journal of Chemistry. 1954; 7(1):87-98.
  2. ^ Waffo AF, Coombes PH, Crouch NR, Mulholland DA, El Amin SM, Smith PJ. Acridone and furoquinoline alkaloids from Teclea gerrardii (Rutaceae: Toddalioideae) of southern Africa. Phytochemistry. 2007 Mar;68(5):663-7. PMID 17174364


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