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Methylenedioxyhydroxymethamphetamine
Systematic (IUPAC) name
(±)-1-(benzo[d][1,3]dioxol-5-yl)-N-hydroxyl-N-methylpropan-2-amine
Identifiers
CAS number 214414-88-7
ATC code  ?
Chemical data
Formula C11H15NO3 
Mol. mass 209.24 g/mol
SMILES eMolecules & PubChem
Therapeutic considerations
Pregnancy cat.  ?
Legal status

3,4-Methylenedioxy-N-hydroxy-N-methylamphetamine (MDHMA; FLEA) is an entactogen, psychedelic, and stimulant of the phenethylamine and amphetamine chemical classes. It is the N-hydroxy homologue of MDMA ("Ecstasy"), and the N-methyl homologue of MDOH. MDHMA was first synthesized and assayed by Alexander Shulgin.[1] In his book PiHKAL (Phenethylamines i Have Known And Loved), Shulgin listed the dosage range as 100–160 mg, and the duration as approximately 4–8 hours.[2] He describes MDHMA as causing entactogenic and open MDMA-like effects, easing communication, and increasing appreciation of the senses.[3]

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FLEA (psychedelic)
Systematic (IUPAC) name
N-(2-Benzo[1,3]dioxol-5-yl-1-methyl-ethyl)-N-methyl-hydroxylamine
Identifiers
CAS number 214414-88-7
ATC code  ?
PubChem  ?
Chemical data
Formula C11H15NO3 
Mol. mass 209.24
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

FLEA, or 3,4-methylenedioxy-alpha,N-dimethyl-N-hydroxyphenethylamine, is a lesser-known psychedelic drug and a substituted amphetamine. It is the N-hydroxy homolog of MDMA (Ecstasy). FLEA was first synthesized by Alexander Shulgin. In his book PiHKAL (Phenethylamines i Have Known And Loved), the dosage range is listed as 100-160mg, and the duration listed as 4-8 hours.[1] FLEA causes entactogenic, open MDMA-like effects and eases communication. It also increases appreciation of the senses. Very little data exists about the pharmacological properties, metabolism, and toxicity of FLEA.

References

External links








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