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forkhead box D3
Symbol FOXD3
Entrez 27022
HUGO 3804
OMIM 611539
RefSeq NM_012183
UniProt Q9UJU5
Other data
Locus Chr. 1 p31.3

Forkhead box D3 also known as FOXD3 is a forkhead protein which in humans is encoded by the FOXD3 gene.[1]


This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain.

Clinical signficance

Mutations in this gene cause vitiligo.[2]


  1. ^ Hromas R, Moore J, Johnston T, Socha C, Klemsz M (June 1993). "Drosophila forkhead homologues are expressed in a lineage-restricted manner in human hematopoietic cells". Blood 81 (11): 2854–9. PMID 8499623.  
  2. ^ Alkhateeb A, Fain PR, Spritz RA (August 2005). "Candidate functional promoter variant in the FOXD3 melanoblast developmental regulator gene in autosomal dominant vitiligo". J. Invest. Dermatol. 125 (2): 388–91. doi:10.1111/j.0022-202X.2005.23822.x. PMID 16098053.  


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