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Fenamic acid
Fenamic acid.png
IUPAC name
Other names N-phenylanthranilic acid
Identifiers
CAS number 91-40-7
PubChem 4386
SMILES
Properties
Molecular formula C13H11NO2
Molar mass 213.23 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Fenamic acid is a molecule which serves as a parent structure for several non-steroidal anti-inflammatory drugs, including mefenamic acid, tolfenamic acid, flufenamic acid, and meclofenamic acid.

This compound may be synthesized by the reaction of 2-chlorobenzoic acid and aniline, with base and copper oxide catalyst in the Goldberg reaction.[1]

GoldmanReaction.svg

The self-condensation of fenamic acid yields acridone.[1]

References

  1. ^ a b C. F. H. Allen and G. H. W. McKee (1943), "Acridone", Org. Synth., http://www.orgsyn.org/orgsyn/orgsyn/prepContent.asp?prep=cv2p0015  ; Coll. Vol. 2: 15  
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