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Feodor Felix Konrad Lynen
Born 6 April 1911
Munich, Germany
Died 6 August 1979 (aged 68)
Munich, Germany
Nationality German
Notable awards Nobel Prize in Physiology or Medicine (1964)

Feodor Felix Konrad Lynen (6 April 1911 – 6 August 1979) was a German biochemist.

Contents

Biography

Feodor Lynen was born in Munich, Germany on 6 April 1911. He started his studies at the chemistry department of Munich University in 1930 and graduated in March 1937 under Heinrich Wieland with the work: "On the Toxic Substances in Amanita". After several years of lecturing there, Lynen became professor at the Munich University in 1947. From 1954 onwards he was director of the Max-Planck Institute for Cellular Chemistry in Munich, which was merged into the newly founded Max-Planck Institute of Biochemistry in 1972.

In 1964 he won the Nobel Prize in Medicine and Physiology together with Konrad Bloch for their discoveries concerning the mechanism and regulation of cholesterol and fatty acid metabolism.[1][2][3][4] He gave his Nobel Lecture on 11 December 1964 titled "The Pathway from Activated Acetic Acid to the Terpenes and Fatty Acids".

Fellowship

The Alexander von Humboldt Foundation has a fellowship named in his honor.

References

  1. ^ Bucher NL, Overath P, Lynen F (June 1960). "beta-Hydroxy-beta-methyl-glutaryl coenzyme A reductase, cleavage and condensing enzymes in relation to cholesterol formation in rat liver". Biochimica et Biophysica Acta 40: 491–501. doi:10.1016/0006-3002(60)91390-1. PMID 13805544.  
  2. ^ Lynen F (July 1966). "[The biochemical basis of the biosynthesis of cholesterol and fatty acids]" (in German). Wiener Klinische Wochenschrift 78 (27): 489–97. PMID 4296920.  
  3. ^ Back P, Hamprecht B, Lynen F (August 1969). "Regulation of cholesterol biosynthesis in rat liver: diurnal changes of activity and influence of bile acids". Archives of Biochemistry and Biophysics 133 (1): 11–21. doi:10.1016/0003-9861(69)90482-2. PMID 5810824.  
  4. ^ Hamprecht B, Nüssler C, Waltinger G, Lynen F (January 1971). "Influence of bile acids on the activity of rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase. 1. Effect of bile acids in vitro and in vivo". European Journal of Biochemistry 18 (1): 10–4. doi:10.1111/j.1432-1033.1971.tb01207.x. PMID 5547468.  

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