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Fesoterodine
Systematic (IUPAC) name
[2-[(1R)-3-(Di(propan-2-yl)amino)-1-phenylpropyl]-4-(hydroxymethyl)phenyl] 2-methylpropanoate
Identifiers
CAS number 286930-03-8
ATC code G04BD11
PubChem 6918558
Chemical data
Formula C 26H37NO3  
Mol. mass 411.278 g/mol
Pharmacokinetic data
Bioavailability 52% (active metabolite)
Protein binding 50% (active metabolite)
Metabolism Hepatic (CYP2D6- and 3A4-mediated)
Half life 7–8 hours (active metabolite)
Excretion Renal (70%) and fecal (7%)
Therapeutic considerations
Licence data

EU EMEA:linkUS FDA:link

Pregnancy cat. C(US)
Legal status Prescription only
Routes Oral

Fesoterodine (INN, brand name Toviaz) is an antimuscarinic drug developed by Schwarz Pharma AG to treat overactive bladder syndrome.[1] It was approved by the European Medicines Agency in April 2007[2] and was approved by the US Food and Drug Administration on October 31, 2008.[3]

Fesoterodine is a prodrug. It is broken down into its active metabolite, 5-hydroxymethyl tolterodine, by plasma esterases.

References








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