The fifth cholera pandemic was the fifth major outbreak of cholera that occurred in the years 1881-1896 starting in India.[1] The 1892 outbreak in Hamburg, Germany was the only major European outbreak; about 8,600 people died in Hamburg. Although generally held responsible for the virulence of the epidemic, the city government went largely unchanged. This was the last serious European cholera outbreak.
The epidemic was serious enough in Rome that Pope Leo XIII built a hospice for afflicted residents inside the Vatican. That building would be torn down in 1996 to make way for construction of the Domus Sanctae Marthae.[2]
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