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Fletazepam
Systematic (IUPAC) name
7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-2,3-dihydro-1,4-benzodiazepine
Identifiers
CAS number 34482-99-0
ATC code none
PubChem 36834
Chemical data
Formula C 17H13ClF4N2  
Mol. mass 356.745
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Fletazepam is a drug which is a benzodiazepine derivative. It has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives, but is mainly notable for its strong muscle relaxant properties.[1]

Fletazepam is most closely related to other N-trifluoroethyl substituted benzodiazepines such as halazepam and quazepam.[2]

See also

References

  1. ^ Barnett, A.; Goldstein, J.; Fiedler, EP.; Taber, RI. (Nov 1974). "The pharmacology of fletazepam a centrally-acting muscle relaxant.". Arch Int Pharmacodyn Ther 212 (1): 164-74. PMID 4476200.  
  2. ^ Iorio, LC.; Barnett, A.; Billard, W. (Jul 1984). "Selective affinity of 1-N-trifluoroethyl benzodiazepines for cerebellar type 1 receptor sites.". Life Sci 35 (1): 105-13. PMID 6738302.  
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