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Flumedroxone: Wikis

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Flumedroxone
Systematic (IUPAC) name
(2R,8S,14S,15S)-14-acetyl-14-hydroxy-2,15-dimethyl-8-(trifluoromethyl)tetracyclo[8.7.0.0 2,7.011,15]heptadec-6-en-5-one
Identifiers
CAS number 987-18-8
ATC code N02CB01
PubChem 71881
Chemical data
Formula C 22H29F3O3  
Mol. mass 398.459 g/mol
Synonyms (6S,10R,13S,17S)-17-acetyl-17-hydroxy-10,13-dimethyl-6-(trifluoromethyl)-2,6,7,8,9,11,12,14,15,16-decahydro-1 H-cyclopenta[a]phenanthren-3-one
17-Acetyloxy-6α-(trifluoromethyl)preg-4-ene-3,20-dione
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Flumedroxone is a corticosteroid derivative used to treat migraines. In one study, the benefit was largely limited to women with headache associated with premenstrual syndrome.[1]

References

  1. ^ Bradley WG, Hudgson P, Foster JB, Newell DJ (August 1968). "Double-blind controlled trial of a micronized preparation of flumedroxone (Demigran) in prophylaxis of migraine". Br Med J 3 (5617): 531–3. PMID 4877801.  
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