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Fluorometholone: Wikis

  

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Fluorometholone
Systematic (IUPAC) name
(1R,2S,8S,10S,11 S,14R,15S,17S)-14-acetyl-1-fluoro-14,17-dihydroxy-2,8,15-trimethyltetracyclo[8.7.0.0 2,7.011,15]heptadeca-3,6-dien-5-one
Identifiers
CAS number 426-13-1
ATC code C05AA06 D07AB06, D07XB04, D10AA01, S01BA07, S01CB05
PubChem 9878
DrugBank APRD00980
Chemical data
Formula C 22H29FO4  
Mol. mass 376.462 g/mol
Synonyms (6S,8S,9R,10S,11S,13 S,14S,17R)-17-acetyl-9-fluoro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[ a]phenanthren-3-one
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat. C
Legal status
Routes  ?

Fluorometholone is a corticosteroid, most often used after laser-based refractive surgery. It is marketed under the brand names FML (Allergan) and Flarex (Alcon).

Fluorometholone acetate ophthalmic suspension is indicated for use in the treatment of steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the eye.

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