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Fluticasone: Wikis


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Systematic (IUPAC) name
S-(fluoromethyl) (6S,8 S,9R,10S,11S,13S,14S,16 R,17R)-
CAS number 90566-53-3
80474-14-2 (propionate)
ATC code D07AC17 & D07AC04 (topical)
PubChem 5311101
DrugBank APRD00065
ChemSpider 4470631
Chemical data
Formula C 22H27F3O4S 
Mol. mass 444.508 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability 0.51% (Intranasal)
Protein binding 91%
Metabolism Intranasal
Hepatic (CYP3A4-mediated)
Half life 10 hours
Excretion Renal
Therapeutic considerations
Pregnancy cat. C for Intranasal and Inhaled
Legal status POM (UK) -only (US)
Routes Intranasal, Inhaled, Topical Cream or Ointment

Fluticasone is a synthetic glucocorticoid.

Both the furoate and propionate forms are used as topical anti-inflammatories:

See also

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