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Fluticasone furoate: Wikis

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Fluticasone furoate
Systematic (IUPAC) name
(6α,11β,16α,17α)-6,9-difluoro-17-{[(fluoro-methyl)thio]carbonyl}-11-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17-yl 2-furancarboxylate
Identifiers
CAS number 80474-14-2
ATC code D07AC17 & R01AD12
PubChem 5311101
DrugBank APRD00065
Chemical data
Formula C 27H29F3O6S 
Mol. mass 538.576 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability 0.51% (Intranasal)
Protein binding 91%
Metabolism Intranasal
Hepatic (CYP3A4-mediated)
Half life 10 hours
Excretion Renal
Therapeutic considerations
Pregnancy cat. C for Intranasal
Legal status POM (UK) -only (US)
Routes Intranasal

Fluticasone furoate is a synthetic corticosteroid derived from fluticasone, marketed by GlaxoSmithKline as Veramyst (US) and Avamys (EU and Canada) for the treatment of allergic rhinitis.

It can be administered by a nasal spray.[1]

References

See also

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