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Formyl peptide receptor 3: Wikis


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Formyl peptide receptor 3
External IDs OMIM136539 MGI1194495 HomoloGene40605 IUPHAR: FPR3 GeneCards: FPR3 Gene
RNA expression pattern
PBB GE FPRL2 214560 at tn.png
More reference expression data
Species Human Mouse
Entrez 2359 14294
Ensembl ENSG00000187474 ENSMUSG00000079700
UniProt P25089 O08790
RefSeq (mRNA) NM_002030 NM_008042
RefSeq (protein) NP_002021 NP_032068
Location (UCSC) Chr 19:
56.99 - 57.02 Mb
Chr 17:
18.02 - 18.11 Mb
PubMed search [1] [2]

N-formyl peptide receptor 3 is a protein that in humans is encoded by the FPR3 gene.[1][2][3]


See also


  1. ^ Bao L, Gerard NP, Eddy RL Jr, Shows TB, Gerard C (Jul 1992). "Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors (FPRH1, FPRH2) to chromosome 19". Genomics 13 (2): 437-40. PMID 1612600.  
  2. ^ Durstin M, Gao JL, Tiffany HL, McDermott D, Murphy PM (Jun 1994). "Differential expression of members of the N-formylpeptide receptor gene cluster in human phagocytes". Biochem Biophys Res Commun 201 (1): 174-9. doi:10.1006/bbrc.1994.1685. PMID 8198572.  
  3. ^ "Entrez Gene: FPRL2 formyl peptide receptor-like 2".  

External links

Further reading

  • Christophe T, Karlsson A, Dugave C, et al. (2001). "The synthetic peptide Trp-Lys-Tyr-Met-Val-Met-NH2 specifically activates neutrophils through FPRL1/lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2.". J. Biol. Chem. 276 (24): 21585–93. doi:10.1074/jbc.M007769200. PMID 11285256.  
  • Yang D, Chen Q, Gertz B, et al. (2002). "Human dendritic cells express functional formyl peptide receptor-like-2 (FPRL2) throughout maturation.". J. Leukoc. Biol. 72 (3): 598–607. PMID 12223529.  
  • Christophe T, Karlsson A, Rabiet MJ, et al. (2002). "Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1/LXA4R, is not affected by lipoxin A4.". Scand. J. Immunol. 56 (5): 470–6. doi:10.1046/j.1365-3083.2002.01149.x. PMID 12410796.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.  
  • Ernst S, Lange C, Wilbers A, et al. (2004). "An annexin 1 N-terminal peptide activates leukocytes by triggering different members of the formyl peptide receptor family.". J. Immunol. 172 (12): 7669–76. PMID 15187149.  
  • Harada M, Habata Y, Hosoya M, et al. (2004). "N-Formylated humanin activates both formyl peptide receptor-like 1 and 2.". Biochem. Biophys. Res. Commun. 324 (1): 255–61. doi:10.1016/j.bbrc.2004.09.046. PMID 15465011.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Kang HK, Lee HY, Kim MK, et al. (2005). "The synthetic peptide Trp-Lys-Tyr-Met-Val-D-Met inhibits human monocyte-derived dendritic cell maturation via formyl peptide receptor and formyl peptide receptor-like 2.". J. Immunol. 175 (2): 685–92. PMID 16002663.  
  • Lee HY, Lee SY, Shin EH, et al. (2007). "F2L, a peptide derived from heme-binding protein, inhibits formyl peptide receptor-mediated signaling.". Biochem. Biophys. Res. Commun. 359 (4): 985–90. doi:10.1016/j.bbrc.2007.06.001. PMID 17577578.  


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